0000000000501333

AUTHOR

Stefano Ursino

0000-0003-3018-2338

showing 2 related works from this author

Can chemotherapy concomitantly delivered with radiotherapy improve survival of patients with resectable rectal cancer? A meta-analysis of literature …

2010

Summary Background There is clear evidence from two systematic reviews that radiotherapy (RT) reduces the risk of local recurrence in patients with resectable rectal cancer, though the data on survival are still equivocal. Objective To assess the effects of chemotherapy combined concomitantly with radiotherapy (CRT) on the increase of overall survival, and on the prevention of local recurrence and distant metastases. Data sources Computerized bibliographic searches of MEDLINE and CANCERLIT (1970–2008) were supplemented with hand searches of reference lists. Study selection Studies were included if they were randomized controlled trials (RCTs) comparing preoperative or postoperative CRT to p…

medicine.medical_specialtySurvivalColorectal cancermedicine.medical_treatmentPopulationAntineoplastic Agentslaw.inventionRectal carcinomaRandomized controlled triallawRisk of mortalityHumansMedicineMeta-analysiRadiology Nuclear Medicine and imagingNeoplasm Metastasiseducationeducation.field_of_studyRadiotherapyRectal Neoplasmsbusiness.industryChemoradiotherapyGeneral Medicinemedicine.diseaseCombined Modality TherapySurgeryRadiation therapyOncologyConcomitantMeta-analysisbusinessPublication BiasChemoradiotherapyCancer Treatment Reviews
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The impact of radiotherapy on survival in resectable gastric carcinoma: A meta-analysis of literature data.

2007

Summary Background The benefit of external radiotherapy for gastric carcinoma has been extensively studied, but data on survival are still equivocal. Objective To assess the effectiveness of surgery combined with preoperative radiotherapy or postoperative chemoradiotherapy in the reduction of all-cause mortality in patients with resectable gastric carcinoma. Methods Computerised bibliographic searches of MEDLINE and CANCERLIT (1970–2006) were supplemented with hand searches of reference lists. Study selection Studies were included if they were randomised controlled trials (RCTs) comparing mortality of surgery combined with preoperative radiotherapy or postoperative chemoradiotherapy to surg…

medicine.medical_specialtySurvivalmedicine.medical_treatmentGastric carcinoma; Meta-analysis; Radiotherapy; SurvivalMEDLINElaw.inventionRandomized controlled triallawStomach NeoplasmsGastric carcinoma; Meta-analysis; Radiotherapy; Survival;medicineCombined Modality TherapyHumansRadiology Nuclear Medicine and imagingMeta-analysiRandomized Controlled Trials as TopicIntention-to-treat analysisRadiotherapybusiness.industryMortality rateGastric carcinomaGeneral MedicineCombined Modality TherapySurgeryRadiation therapyOncologyMeta-analysisRadiotherapy AdjuvantbusinessChemoradiotherapy
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