0000000000511303

AUTHOR

Sven Schröder

showing 2 related works from this author

Coptis chinensis Franch. exhibits neuroprotective properties against oxidative stress in human neuroblastoma cells.

2014

Abstract Ethnopharmacological relevance The dried rhizome of Coptis chinensis Franch. (family Ranunculaceae ) is traditionally used in Chinese medicine for the treatment of inflammatory diseases and diabetes. Recent studies showed a variety of activities of Coptis chinensis Franch. alkaloids, including neuroprotective, neuroregenerative, anti-diabetic, anti-oxidative and anti-inflammatory effects. However, there is no report on the neuroprotective effect of Coptis chinensis Franch. watery extract against tert -butylhydroperoxide ( t -BOOH) induced oxidative damage. The aim of the study is to investigate neuroprotective properties of Coptis chinensis Franch. rhizome watery extract (CRE) and …

SH-SY5YTime FactorsCell SurvivalApoptosisPharmacologymedicine.disease_causeNeuroprotectionNeuroblastomatert-ButylhydroperoxideCell Line TumorDrug DiscoveryMedicineHumansViability assayPharmacologychemistry.chemical_classificationMembrane Potential MitochondrialReactive oxygen speciesbiologyTraditional medicinebusiness.industryPlant ExtractsReverse Transcriptase Polymerase Chain ReactionCoptis chinensisbiology.organism_classificationMicroarray AnalysisOxidative StressNeuroprotective AgentschemistryApoptosisbusinessReactive Oxygen SpeciesTXNIPOxidative stressRhizomeCoptisJournal of ethnopharmacology
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Objectifying acupuncture effects by lung function and numeric rating scale in patients undergoing heart surgery.

2012

Rationale. Poststernotomy pain and impaired breathing are common clinical problems in early postoperative care following heart surgery. Insufficiently treated pain increases the risk of pulmonary complications. High-dose opioids are used for pain management, but they may cause side effects such as respiratory depression.Study Design. We performed a prospective, randomized, controlled, observer-blinded, three-armed clinical trial with 100 patients. Group 1 (n=33) and Group 2 (n=34) received one 20 min session of standardized acupuncture treatment with two different sets of acupoints. Group 3 (n=33) served as standard analgesia control without additional intervention. Results. Primary endpoin…

medicine.medical_specialtyVital capacityArticle Subjectbusiness.industryAnalgesiclcsh:Other systems of medicinelcsh:RZ201-999Pulmonary function testingSurgeryClinical trialFEV1/FVC ratioComplementary and alternative medicineStatistical significanceAcupuncturemedicineClinical endpointbusinessResearch ArticleEvidence-based complementary and alternative medicine : eCAM
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