0000000000512972

AUTHOR

Akos Varga-szemes

showing 3 related works from this author

Coronary plaque assessment of Vasodilative capacity by CT angiography effectively estimates fractional flow reserve.

2021

Abstract Background To evaluate the feasibility of non-invasive fractional flow reserve (FFR) estimation using histologically-validated assessment of plaque morphology on coronary CTA (CCTA) as inputs to a predictive model further validated against invasive FFR. Methods Patients (n = 113, 59 ± 8.9 years, 77% male) with suspected coronary artery disease (CAD) who had undergone CCTA and invasive FFR between August 2013 and May 2018 were included. Commercially available software was used to extract quantitative plaque morphology inclusive of both vessel structure and composition. The extracted plaque morphology was then fed as inputs to an optimized artificial neural network to predict lesion-…

Malemedicine.medical_specialtyComputed Tomography AngiographyFractional flow reserveCoronary Artery Disease030204 cardiovascular system & hematologyCoronary AngiographySeverity of Illness IndexCross-validationCoronary artery disease03 medical and health sciences0302 clinical medicinePredictive Value of TestsInternal medicinemedicineHumansPlaque morphology030212 general & internal medicineRetrospective Studiesmedicine.diagnostic_testbusiness.industryArea under the curveCoronary Stenosismedicine.diseaseRegressionFractional Flow Reserve MyocardialStenosisAngiographyCardiologyFemaleCardiology and Cardiovascular MedicinebusinessInternational journal of cardiology
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Right/Left Ventricular Blood Pool T2 Ratio as an Innovative Cardiac MRI Screening Tool for the Identification of Left‐to‐Right Shunts in Patients Wit…

2021

Background Left-to-right (L-R) shunts are characterized by a pathological connection between high- and low-pressure systems, leading to a mixing of oxygen-rich blood with low oxygenated blood. They are typically diagnosed by phase-contrast cardiac magnetic resonance imaging (MRI) which requires extensive planning. T2 is sensitive to blood oxygenation and may be able to detect oxygenation differences between the left (LV) and right ventricles (RV) caused by L-R shunts. Purpose To test the feasibility of routine T2 mapping to detect L-R shunts. Study type Retrospective. Population Patients with known L-R shunts (N = 27), patients with RV disease without L-R shunts (N = 21), and healthy volunt…

medicine.medical_specialtyeducation.field_of_studyImaging biomarkerReceiver operating characteristicmedicine.diagnostic_testbusiness.industryPopulationMagnetic resonance imagingOxygenationCardiac magnetic resonance imagingInternal medicineCardiologyMedicineRadiology Nuclear Medicine and imagingStage (cooking)businesseducationShunt (electrical)Journal of Magnetic Resonance Imaging
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Myocardial Mass Corrected CMR Feature Tracking-Based Strain Ratios are Different in Pathologies With Increased Myocardial Mass

2020

Acute myocarditis (AM) and hypertensive heart disease (HHD) have different pathophysiological backgrounds, thus potentially showing distinct patterns of altered myocardial deformation. Therefore, CMR left ventricular (LV) feature tracking (FT)- based strain parameters were indexed to myocardial mass index (LVMi) in order to evaluate potential additional value in the differentiation among AM, HHD, and healthy volunteers (HV) compared to non-indexed conventional strain.Patients with AM (n = 43) and HHD (n = 28) underwent CMR at 3T. 61 HV served as controls. Cine imaging-based FT-strain analysis was performed and natural strain (nStrain) values were evaluated for gender and age specific differ…

Malemedicine.medical_specialtyHeart VentriclesMagnetic Resonance Imaging CineSensitivity and SpecificityVentricular Function Left030218 nuclear medicine & medical imagingAge and gender03 medical and health sciences0302 clinical medicinePredictive Value of TestsInternal medicineHealthy volunteersmedicineHumansRadiology Nuclear Medicine and imagingMyocardial massStrain (chemistry)business.industryMyocardiummedicine.diseaseHypertensive heart diseaseMyocarditisAcute myocarditisCine imaging030220 oncology & carcinogenesisCardiologyFeature trackingFemalebusinessAcademic Radiology
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