0000000000519524

AUTHOR

Hans Rolf Jäger

showing 2 related works from this author

Cerebral Microbleeds and Long-Term Cognitive Outcome: Longitudinal Cohort Study of Stroke Clinic Patients

2012

<i>Background:</i> Vascular cognitive impairment causes significant disability in the elderly and is common following ischaemic stroke. Although the underlying mechanisms and prognostic factors remain unclear, small vessel diseases are known to contribute. Cerebral microbleeds (CMBs) are a magnetic resonance imaging (MRI) manifestation of small vessel diseases and may contribute to vascular cognitive impairment, particularly frontal-executive functions. We hypothesized that baseline CMBs would predict long-term cognitive outcome, specifically frontal-executive function. <i>Methods:</i> A cohort of consecutive patients found to have CMBs when first referred to a strok…

AdultMalemedicine.medical_specialtyNeuropsychological TestsCohort StudiesExecutive FunctionCognitionInternal medicinemedicineHumansLongitudinal StudiesNeuropsychological assessmentCognitive declineVascular dementiaStrokeAgedCerebral HemorrhageAged 80 and overIntelligence TestsSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicamedicine.diagnostic_testbusiness.industryMagnetic resonance imagingCognitionCerebral InfarctionMiddle Agedmedicine.diseaseMagnetic Resonance ImagingStrokeNeurologymicrobleedsCohortPhysical therapyFemaleNeurology (clinical)Verbal memoryCognition DisordersCardiology and Cardiovascular MedicinebusinessPsychomotor PerformanceFollow-Up StudiesCerebrovascular Diseases
researchProduct

Prevalence and Cognitive Impact of Medial Temporal Atrophy in a Hospital Stroke Service: Retrospective Cohort Study

2015

Background Cerebrovascular disease and neurodegeneration cause cognitive impairment and frequently coexist. Aims Our objectives were to investigate the prevalence and cognitive impact of medial temporal lobe atrophy – a radiological marker often associated with Alzheimer's disease – in a hospital stroke service. Methods Retrospective cohort study of patients from a hospital stroke service. Patients assessed for suspected ischemic stroke or transient ischemic attack, irrespective of final diagnosis, underwent neuropsychological testing and magnetic resonance imaging. medial temporal lobe atrophy, white matter hyperintensities, lacunes, and cerebral microbleeds were rated using established cr…

Malemedicine.medical_specialtyPathologyPopulationNeuropsychological TestsSeverity of Illness IndexBrain IschemiaInternal medicinePrevalencemedicineHumansCerebral amyloid angiopathyeducationVascular dementiaStrokeRetrospective Studieseducation.field_of_studymedicine.diagnostic_testbusiness.industryMagnetic resonance imagingRetrospective cohort studyOdds ratioMiddle Agedmedicine.diseaseMagnetic Resonance ImagingTemporal LobeHyperintensityHospitalizationStrokeLogistic ModelsNeurologyMultivariate AnalysisCardiologyFemaleAtrophyVerbal memoryCognition DisordersbusinessMedial temporal lobe atrophyInternational Journal of Stroke
researchProduct