Author: Michael Nuernberg

0000000000520359

AUTHOR

Michael Nuernberg

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The COGNITION Study Rationale and Design: Influence of Closed Loop Stimulation on Cognitive Performance in Pacemaker Patients

2008

Background: Several studies showed the beneficial effect of pacemaker implantation on cognitive performance in patients with bradycardia. But it has never been investigated if patients with chronotropic incompetence may improve their cognitive performance if treated by a rate-adaptive system reacting to mental stress in comparison to the most frequently used accelerometer-driven pacing. Methods: The randomized, single-blind, multicenter COGNITION study evaluates if closed loop stimulation (CLS) offers incremental benefit in the speed of cognitive performance and the overall well-being of elderly patients with bradycardia compared with accelerometer-based pacing. Four hundred chronotropicall…

BradycardiaPacemaker Artificialmedicine.medical_specialtybusiness.industryChronotropic incompetenceBiofeedback PsychologyAtrial fibrillationCognitionGeneral Medicinemedicine.diseaseClosed loop stimulationQuality of lifeGermanyAtrial FibrillationPhysical therapyHumansMedicineEffects of sleep deprivation on cognitive performancemedicine.symptomCognition DisordersCardiology and Cardiovascular MedicinebusinessAdverse effectRandomized Controlled Trials as TopicPacing and Clinical Electrophysiology

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