0000000000521629
AUTHOR
Enrico Pace
Cigarette smoke upregulates TLR4 expression and enhances TLR4 mediated responses
Cigaretta smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses
the expression of innate immunity and coagulative response in acute lung injury. septic verus non septic patients.
Elevated expression of prostaglandin receptor and increased release of prostaglandin E maintain the survival of CD45RO T cells in the inflamed human pleural space.
Counteracting effects of apigenin and leptin on lung adenocarcinoma cells.
Altered expression of TLR4 and beta 2 defensin in chronic obstructive pulmonary disease
Hypoallergenic fragment of Parj 2 increases functional expression of toll like receptor in atopic children
Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses
THE M3 MUSCARINIC RECEPTOR IS INVOLVED IN THE ACTIVATION OF AIRWAY EPITHELIUM IN VITRO
La risposta immune neella insufficienza respiratoria acuta in terapia intensiva: correlazione tra scores clinici e markers bioumorali
Alterated expression of leptin and its receptor in the epithelium of asthmatic patients
In vivo and in vitro effects of variants Parj2 in asthmatic children
Cigarette smoke increases TLR4 expression and modifies LPS mediated responses in airway epithelial cells.
Pleural mesothelial cells express both BLT2 and PPARa and mount an integrated response to pleural LTB4
Reduced apoptosis of CD8+ T-lymphocytes in the airways of mild COPD patients.
Multiple synergystic effects of fluticasone propionate and salmeterol on T lymphocyte activation in asthma
Lung Immune and Coagulative Host Response in Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease (aeocpd).
Role of PGE2 in the invasiveness, growth and protection of cancer cells in malignant pleuritis
Abstract The recurrence of pleural effusions is a common event in a variety of neoplastic diseases. The objective of this study was to identify the mechanisms promoting the homing and growth of cancer cells within the pleural space. A cancer cell line recovered from malignant pleural fluids (lung adenocarcinoma cell line) that constitutively expresses cyclooxygenase 2 (COX-2) and all types of prostaglandin receptors was studied. It was first demonstrated using a matrigel system, that malignant pleural fluids increase the invasiveness of adenocarcinoma cells more than congestive heart failure (CHF) pleural fluids. Moreover, exposure to exudative malignant, but not to CHF pleural fluids, incr…
The expression of innate immunity and coagulative response in acute lung injury.Septic vs non sepstic patients.
Pleural LTB4 upregulates ICAM-1 molecules via STAT-1 activation on pleural mesothelial cells
LTB4 is present in exudative pleural effusions and contributes actively to neutrophil recruitment in the inflamed pleural space
SUMMARY The pleural space is a virtual compartment between the lung and chest wall that becomes filled with fluid and inflammatory cells during a variety of respiratory diseases. Here, we study the potential role of the eicosanoid metabolite leukotriene B4 (LTB4) in disparate diseases leading to acute (pneumonia) or chronic (tuberculosis, cancer) inflammation of the pleural space. LTB4 concentrations were significantly higher in pleural fluid due to pneumonia, tuberculosis and cancer with respect to congestive heart failure and correlated with neutrophil elastase, which is used as an indication of state of activation of neutrophils in the pleural space. Moreover, pleural LTB4 was biological…