0000000000523012
AUTHOR
Francisco Silva
Ion transport through polyelectrolyte multilayers under steady-state conditions
Abstract The permeability of a self-assembled polyelectrolyte multilayer to small ions under the influence of an applied potential difference is studied as a function of the number of layers and the nature of the supporting electrolyte. The multilayer is described as a series of homogeneously charged membranes with alternating sign of their fixed charge. Ion transport is described on the basis of the diffusion equation and the assumption of (Donnan) electrochemical equilibrium at the boundaries between layers. The calculated steady-state current–voltage curves are found to be in good agreement with experimental linear sweep voltammograms (at low sweep rate). The permeability of polystyrenes…
Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Background The European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (FHSC) global registry provides a platform for the global surveillance of familial hypercholesterolaemia through harmonisation and pooling of multinational data. In this study, we aimed to characterise the adult population with heterozygous familial hypercholesterolaemia and described how it is detected and managed globally. Methods Using FHSC global registry data, we did a cross-sectional assessment of adults (aged 18 years or older) with a clinical or genetic diagnosis of probable or definite heterozygous familial hypercholesterolaemia at the time they were entered into the registries. Dat…
Analysis of adsorption of phospholipids at the 1,2-dichloroethane/water interface by electrochemical impedance spectroscopy: A study of the effect of the saturated alkyl chain
Abstract The adsorption behaviour of a series of phosphatidylcholines (PCs) with saturated carbon chains of different length (DLPC, DPPC, DSPC, DAPC, and DBPC) at the electrified 1,2-dichloroethane/water interface was studied by measuring electrochemical impedance spectroscopy at the polarized interface. Two different trends in the interfacial capacitance were observed for any of the PCs the capacity dependence on the applied potential: strong adsorption occurs at negative potential with a marked decrease of C ( E ); increase of capacity is observed at positive potentials. It is demonstrated that the interfacial lipid adsorption was dependent on phospholipid concentration, applied potential…