0000000000525675

AUTHOR

Luigi Di Biase

0000-0001-6508-4047

showing 2 related works from this author

Incremental value and safety of oral ivabradine for heart rate reduction in computed tomography coronary angiography

2012

Background: Heart rate (HR) reduction is essential to achieve optimal image quality and diagnostic accuracy with computed tomography coronary angiography (CTCA). Administration of ivabradine could be an attractive alternative to beta-blockade to reduce HR. Methods: One-hundred-twenty-three patients referred for CTCA were prospectively enrolled. Patients were divided in two groups depending on the absence or presence of chronic beta-blockade treatment. Within the two groups patients were randomized to either no additional premedication or oral ivabradine for 5 days prior to CTCA. In presence of chronic beta-blockade therapy it was shifted to atenolol 50 mg twice a day for 5 days prior to CTC…

MaleCoronary angiographymedicine.medical_specialtyAdministration OralComputed tomographyCoronary Artery DiseaseCoronary AngiographyComputed tomography coronary angiographyHeart RateInternal medicineHeart rateBradycardiamedicineHumansIvabradineIn patientProspective StudiesHeart rate reductionAgedmedicine.diagnostic_testbusiness.industryBenzazepinesMiddle AgedAtenololCoronary heart diseaseBlood pressureAnesthesiaCardiologyFemalePremedicationTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessIvabradinemedicine.drugInternational Journal of Cardiology
researchProduct

Heart rate control with oral ivabradine in computed tomography coronary angiography: a randomized comparison of 7.5 mg vs 5 mg regimen.

2013

Background: Heart rate (HR) reduction is essential to achieve optimal image quality and diagnostic accuracy with computed tomography coronary angiography (CTCA). Administration of oral ivabradine seems to be more effective than beta-blockade in reducing HR in patients referred for CTCA. Methods: Two-hundred-fifty-nine consecutive patients referred for CTCA were prospectively enrolled. Patients not receiving beta-blocker at baseline (group 1) and those with beta-blocker therapy (group 2) were enrolled in the study. Each group was randomized into 3 parallel arms with 1:1:1 allocation. Patients who did not receive beta-blocker at baseline: underwent CTCA without beta blocker (n=49), and receiv…

Coronary angiographyMalemedicine.medical_specialtymedicine.drug_classAdministration OralComputed tomographyCoronary Artery DiseaseCoronary AngiographyComputed tomography coronary angiographyCohort StudiesHeart RateInternal medicineHeart ratemedicineHumansIvabradineProspective StudiesHeart rate reductionBeta blockerDose ModificationAgedRetrospective Studiesmedicine.diagnostic_testDose-Response Relationship Drugbusiness.industryBenzazepinesMiddle AgedCoronary heart diseaseRegimenBlood pressureAnesthesiaCardiologyFemaleCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedIvabradinemedicine.drug
researchProduct