0000000000527756
AUTHOR
Neira Chaparro
showing 2 related works from this author
pH and salivary sodium bicarbonate during the administration protocol for methotrexate in children with leukemia
2007
Objective: To analyze the behavior of pH and sodium bicarbonate (NAHCO3) in the saliva of patients with leukemia during the administration protocol for Methotrexate (Mtx). Materials and Methods: A controlled clinical essay was carried out on 23 patients between 4 and 18 years of age with high-risk Acute Lymphoblastic Leukemia. Sampling was carried out at To : basal condition; T1 : 12 hours after intravenous administration of sodium bicarbonate, before administering Mtx and T2 : 3 hours after administering Mtx, the time of maximum concentration. Chiron-Diagnostic 378® equipment was used to determine pH and sodium bicarbonate. The data was interpreted using Analysis of Variance at the 5% sign…
pH and salivary sodium bicarbonate in cancer patients : correlation with seric concentration
2008
Objective: To determine the correlation between pH and bicarbonate of soda in blood and saliva in child and adolescent patients during the administration of 3g/m2 of methotrexate. Method: A controlled clinical test was performed on 23 patients diagnosed with Acute Lymphoblastic Leukemia. Ages ranged from 4 to 18. The Spearman Correlation Coefficient was used to interpret the data. Results: No significant correlation was found between pH levels and seric and salivary sodium bicarbonate. However, there was a significant correlation between the levels of sodium bicarbonate in the body fluids evaluated (rs 0.2576, p=0.0354). Conclusions: Changes modifying the microenvironment of the oral cavity…