0000000000529598

AUTHOR

Richard W. Hagan

showing 2 related works from this author

CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content

2020

Shotgun metagenomics applied to archaeological feces (paleofeces) can bring new insights into the composition and functions of human and animal gut microbiota from the past. However, paleofeces often undergo physical distortions in archaeological sediments, making their source species difficult to identify on the basis of fecal morphology or microscopic features alone. Here we present a reproducible and scalable pipeline using both host and microbial DNA to infer the host source of fecal material. We apply this pipeline to newly sequenced archaeological specimens and show that we are able to distinguish morphologically similar human and canine paleofeces, as well as non-fecal sediments, fro…

dogsArcheologyMicrobial DNAData Mining and Machine LearningCoprolitemicrobiomeendogenous DNAlcsh:MedicineMorphology (biology)Genomechemistry.chemical_compoundPaleofecesDog0601 history and archaeologyGutArqueologia Metodologia0303 health sciences060102 archaeologyGeneral NeuroscienceGeneral Medicine06 humanities and the artsGenomicsNextflowmachine learningnextflowgutGeneral Agricultural and Biological SciencesShotgun metagenomicsPaleofecesHumanpaleofecesBioinformaticsBiologyMicrobiologyGeneral Biochemistry Genetics and Molecular Biologydiversity03 medical and health sciencesEndogenous DNAMachine learningcoprolitedog molecular analysishumanMicrobiomeancient DNAgenome030304 developmental biology030306 microbiologyHost (biology)lcsh:RcultureAncient DNAarcheologychemistryEvolutionary biologyAnthropologyCoproliteMicrobiomedietDNAPeerJ
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Exotic foods reveal contact between South Asia and the Near East during the second millennium BCE

2020

Aunque el papel clave del comercio a larga distancia en la transformación de las cocinas en todo el mundo está bien documentado desde al menos la época romana, la prehistoria del comercio de alimentos euroasiático es menos visible. Con el fin de arrojar luz sobre la transformación de las cocinas del Mediterráneo oriental durante la Edad del Bronce y la Edad del Hierro Temprana, analizamos los microrestos y las proteínas conservadas en el cálculo dental de individuos que vivieron durante el segundo milenio a. Nuestros resultados proporcionan evidencia clara del consumo de alimentos básicos esperados, como cereales (Triticeae), sésamo ( Sesamum ) y dátiles ( Phoenix ). Además, informamos evid…

Mediterranean climateAsiaSouthern LevantDried fruitHuman MigrationSocial Sciences930Ancient historyDNA MitochondrialPrehistoryAlte Geschichte Vor- und Frühgeschichte ArchäologieMiddle EastAsian PeopleBronze AgeOther parts of ancient world (Antiquity) [R939]HumansDental CalculusHistory AncientMultidisciplinaryMiddle EastFossilsGenome HumanHistory of the ancient world to ca. 499 [T930]Restes de plantes (Arqueologia)CommercePrehistoric Archaeology [FVFG]Spice tradeGeographyArchaeologyFoodIron AgeGreece (Antiquity) [R938]Food Analysis
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