0000000000530497

AUTHOR

D. Cox

showing 5 related works from this author

Assessment of blood coagulation in severe liver disease using thromboelastography: use of citrate storage versus native blood.

2003

Thromboelastography evaluates the viscoelastic properties of blood coagulation. Using native blood, measurement must start soon after sampling. With normal coagulation, native and citrated blood values correlate well. No data exists from cirrhotic patients. We compared native and citrate thromboelastography parameters in 30 cirrhotic patients (20 Child-Pugh C class, two liver failure). Thromboelastography was performed within 4 min using native blood and after recalcification within 1-2 h of citrate storage. Thromboelastography variables (r, a, k, ma) were compared using the Mann-Whitney test, correlation investigated with the Pearson method and the degree of agreement with the Bland-Altman…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisTime FactorsInsuficiencia hepaticaGastroenterologyLiver diseaseInternal medicinemedicineHumansCitratesBlood CoagulationAgedHepatitis Chronicmedicine.diagnostic_testbusiness.industryLiver DiseasesSignificant differenceLiver failureHematologyGeneral MedicineMiddle Agedmedicine.diseaseThromboelastographySurgeryThrombelastographyCoagulationFemaleBlood Coagulation TestsbusinessLiver FailureBlood coagulationfibrinolysis : an international journal in haemostasis and thrombosis
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Spectroscopic Tools Applied to Element Z = 115 Decay Chains

2014

Nuclides that are considered to be isotopes of element Z = 115 were produced in the reaction 48Ca + 243Am at the GSI Helmholtzzentrum für Schwerionenforschung Darmstadt. The detector setup TASISpec was used. It was mounted behind the gas-filled separator TASCA. Thirty correlated α-decay chains were found, and the energies of the particles were determined with high precision. Two important spectroscopic aspects of the offline data analysis are discussed in detail: the handling of digitized preamplified signals from the silicon strip detectors, and the energy reconstruction of particles escaping to upstream detectors relying on pixel-by-pixel dead-layer thicknesses.

PhysicsIsotopeSiliconPhysics::Instrumentation and DetectorsPhysicsQC1-999DetectorSeparator (oil production)Mechanical engineeringchemistry.chemical_element7. Clean energyNuclear physicschemistryPhysical SciencesSubatomic Physicsddc:530Decay chainNuclideNuclear ExperimentLine (formation)EPJ Web of Conferences
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Identification of sub-μs isomeric states in the odd-odd nucleus 178Au

2021

The neutron-deficient gold (Z=79) isotopes in the vicinity of the neutron midshell N=104 provide prolific examples of shape coexistence and isomerism at low excitation energy. They can be probed via a number of different experimental techniques. In this study, two new isomeric states with half-lives of 294(7) and 373(9) ns have been observed in the neutron-deficient odd-odd nuclide 178Au (N=99) in an experiment at the RITU gas-filled separator at JYFL, Jyväskylä. This result was achieved due to the use of a segmented planar germanium detector with a high efficiency at low energies. By applying the recoil-decay tagging technique, they were assigned to decay to two different long-lived α-deca…

isotoopit3106Nuclear Experimentydinfysiikkakulta
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Production cross section and decay study of $^{243}$Es and $^{249}$Md

2019

In the study of the odd-$Z$, even-$N$ nuclei $^{243}$Es and $^{249}$Md, performed at the University of Jyv\"askyl\"a, the fusion-evaporation reactions $^{197}$Au($^{48}$Ca,2$n$)$^{243}$Es and $^{203}$Tl($^{48}$Ca,2$n$)$^{249}$Md have been used for the first time. Fusion-evaporation residues were selected and detected using the RITU gas-filled separator coupled with the focal-plane spectrometer GREAT. For $^{243}$Es, the recoil decay correlation analysis yielded a half-life of $24 \pm 3$s, and a maximum production cross section of $37 \pm 10$ nb. In the same way, a half-life of $26 \pm 1$ s, an $\alpha$ branching ratio of 75 $\pm$ 5%, and a maximum production cross section of 300 $\pm$ 80 nb…

ydinreaktiotalpha decayNuclear ReactionsFOS: Physical scienceslow and intermediate energy heavy-ion reactionsNuclear Experiment (nucl-ex)[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]Nuclear Experiment
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