0000000000530994

AUTHOR

Simon Herkenrath

showing 2 related works from this author

Obstructive sleep apnoea in acute coronary syndrome.

2019

Obstructive sleep apnoea (OSA) syndrome affects about 13% of the male and 7–9% of the female population. Hypoxia, oxidative stress and systemic inflammation link OSA and cardiovascular and metabolic consequences, including coronary artery disease. Current research has identified several clinical phenotypes, and the combination of breathing disturbances during sleep, systemic effects and end-organ damage might help to develop personalised therapeutic approaches. It is unclear whether OSA is a risk factor for acute coronary syndrome (ACS) and might affect its outcome. On the one hand, OSA in patients with ACS may worsen prognosis; on the other hand, OSA-related hypoxaemia could favour the dev…

Pulmonary and Respiratory MedicineMaleAcute coronary syndromemedicine.medical_specialtymedicine.medical_treatmentSettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematologySystemic inflammationCoronary artery disease03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinePositive airway pressurePrevalenceMedicineHumansContinuous positive airway pressureNon disponibiliAcute Coronary SyndromeAdverse effectLunglcsh:RC705-779Sleep Apnea ObstructiveContinuous Positive Airway Pressurebusiness.industryRespirationHemodynamicsSleep apnealcsh:Diseases of the respiratory systemHypoxia (medical)medicine.diseasenervous system diseasesrespiratory tract diseasesTreatment Outcome030228 respiratory systemCardiologyPatient ComplianceFemalemedicine.symptombusinessSleepEuropean respiratory review : an official journal of the European Respiratory Society
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Evaluation of a multicomponent grading system for obstructive sleep apnoea: the Baveno classification

2021

New findings on pathophysiology, epidemiology, and outcome have raised concerns on the relevance of the apnoea–hypopnoea index (AHI) in the classification of obstructive sleep apnoea (OSA) severity. Recently, a multicomponent grading system decision integrating symptomatology and comorbidities (Baveno classification), was proposed to characterise OSA and to guide therapeutic decisions. We evaluated whether this system reflects the OSA population, whether it translates into differences in outcomes, and whether the addition of AHI improves the scheme. A total of 14 499 OSA patients from the European Sleep Apnoea Database cohort were analysed. The groups were homogeneously distributed and were…

Pulmonary and Respiratory Medicinemedicine.medical_specialty5RulesPopulationMEDLINElcsh:Medicine03 medical and health sciencesPrevalent0302 clinical medicinestomatognathic systemHypopneaInternal medicineEpidemiologymedicineResistant Hypertensioneducationeducation.field_of_studybusiness.industrylcsh:ROriginal Articlesnervous system diseasesrespiratory tract diseases[SDV] Life Sciences [q-bio]Blood pressure030228 respiratory systemPositive Airway PressureCohortHuman medicineTreatment decision makingSleepbusiness030217 neurology & neurosurgeryERJ Open Research
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