0000000000535734
AUTHOR
Fabbri A.
Accuracy of pre-hospital triage tools for major trauma: a systematic review with meta-analysis and net clinical benefit
Abstract Background We conducted a systematic review to evaluate and compare the accuracy of pre-hospital triage tools for major trauma in the context of the development of the Italian National Institute of Health guidelines on major trauma integrated management. Methods PubMed, Embase, and CENTRAL were searched up to November 2019 for studies investigating pre-hospital triage tools. The ROC (receiver operating characteristics) curve and net clinical benefit for all selected triage tools were performed. Quality assessment was performed using the Quality Assessment of Diagnostic Accuracy Studies–2. Certainty of the evidence was judged with the Grading of Recommendations Assessment, Developme…
Histological studies on pistacio vegetative organs as related to fructification
Histological Studies on Pistachio Vegetative Organs as Related to Fructification Effects of fruiting on histological structure and histochemical characteristics of shoots, leaves and roots of pistachio (Pistacia vera L.) were microscopically examined on tissues sampled from trees with different crop-loads and carbohydrate reserves availability (bearing, non-bearing and trees subjected to inflorescence-bud removal twenty days before full bloom for four consecutive years). Differences in cambium activity and xylem and phloem structure in several developmental stages are reported. Starch content was higher in “deblossomed” than in non-bearing and bearing trees.
Clinical practice guideline for the integrated management of major trauma by the Italian National Institute of Health: process and methods
Background. Major trauma describes serious injuries requiring lifesaving interventions or resulting in long-term disability; it represents about 8% of all deaths worldwide. Specific guidelines can help reduce deaths and disabilities, provided they adhere to high quality and trustworthiness standards. This article aims at introducing the development process of the Istituto Superiore di Sanità, ISS (Italian National Institute of Health) guideline for major trauma integrated management. Methods. We applied the ISS methodological standards including the GRADE-ADOLOPMENT approach for adoption, adaptation, and de novo development of trustworthy guidelines. Results. The scope was formulated by the…
Resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major trauma and uncontrolled haemorrhagic shock: a systematic review with meta-analysis
AbstractBackgroundMultiple studies regarding the use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in patients with non-compressible torso injuries and uncontrolled haemorrhagic shock were recently published. To date, the clinical evidence of the efficacy of REBOA is still debated. We aimed to conduct a systematic review assessing the clinical efficacy and safety of REBOA in patients with major trauma and uncontrolled haemorrhagic shock.MethodsWe systematically searched MEDLINE (PubMed), EMBASE and CENTRAL up to June 2020. All randomized controlled trials and observational studies that investigated the use of REBOA compared to resuscitative thoracotomy (RT) with/witho…