0000000000539003

AUTHOR

A. Bove

showing 3 related works from this author

The impact of DAA-mediated HCV eradication on CD4+ and CD8+ T lymphocyte trajectories in HIV/HCV coinfected patients: Data from the ICONA Foundation …

2021

HCV infection has been hypothesized as a contributor of poor CD4+ recovery in patients living with HIV (PLWHIV). Aim of this study was to evaluate CD4+, CD8+ cells and CD4/CD8 ratio trends before and after HCV treatment with direct acting agents (DAA) in PLWHIV. HIV/HCV patients enrolled in ICONA and HepaICONA cohorts with HIV-RNA≤50 copies/ml who achieved a sustained viral response after DAA treatment were studied. A linear regression model was used to investigate CD4+, CD8+ and CD4/CD8 changes 12 months before and after DAA treatment. A total of 939 HIV/HCV patients were included, 225 (24.0%) female, median age: 53 years (IQR 50–56). At DAA initiation, CD4+ T cell count was <350 cells/…

CD4-Positive T-LymphocytesHIV InfectionsHepacivirusCD8-Positive T-LymphocytesGastroenterologySettore MED/07chemistry.chemical_compound0302 clinical medicineCd8 t lymphocyteHIV Infection030212 general & internal medicineCoinfectionCD4; CD8; DAA; HCV/HIV; immune activationHcv clearancevirus diseasesMiddle AgedHepatitis CInfectious Diseasesmedicine.anatomical_structureCD4-Positive T-LymphocyteCohort030211 gastroenterology & hepatologyFemaleCD4 CD8 DAA HCV/HIV immune activationHumanImmune activationmedicine.medical_specialtyHCV/HIVT cellAntiviral Agentsimmune activationNO03 medical and health sciencesVirologyInternal medicinemedicineHumansIn patientimmune activation.DAAAntiviral AgentHepaciviruHepatologybusiness.industryRibavirinCD8-Positive T-LymphocyteCD8CD4CD4 Lymphocyte CountchemistryCD4; CD8; DAA; HCV/HIV; immune activation; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Hepacivirus; Humans; Middle Aged; Coinfection; HIV Infections; Hepatitis CbusinessCD8
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The THYCOVIT (Thyroid Surgery during COVID-19 pandemic in Italy) study: results from a nationwide, multicentric, case-controlled study

2021

AbstractThe outbreak of the COVID-19 pandemic has led to a disruption of surgical care. The aim of this multi-centric, retrospective study was to evaluate the impact of the pandemic on surgical activity for thyroid disease among the Italian Units of Endocrine Surgery. Three phases of the pandemic were identified based on the epidemiological situation and the public measures adopted from the Italian Government (1st phase: from 9th March to 3rd May 2020; 2nd phase: from 4th May to 14th June; 3rd phase: from 15th June to 31st). The patients operated upon during these phases were compared to those who underwent surgery during the same period of the previous year. Overall, 3892 patients from 28 …

COVID-19; Endocrine surgery; SARS-CoV-2; Thyroid carcinoma; Thyroidectomymedicine.medical_specialtymedicine.medical_treatmentThyroid GlandCOVID-19; Endocrine surgery; SARS-CoV-2; Thyroid carcinoma; Thyroidectomy; Humans; Italy; Retrospective Studies; SARS-CoV-2; COVID-19; Pandemics; Thyroid GlandNOThyroid carcinomaRetrospective StudiePandemicEpidemiologymedicineHumansThyroid cancerPandemicsLS7_4Retrospective StudiesPandemicbusiness.industrySARS-CoV-2Thyroid diseaseThyroidectomyCase-control studyCOVID-19Retrospective cohort studymedicine.diseaseSurgeryEndocrine surgeryEndocrine surgeryItalyThyroidectomyOriginal ArticleSurgerybusinessHuman
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Impact of the COVID-19 pandemic on surgery for thyroid cancer in Italy: nationwide retrospective study

2021

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2019-20 coronavirus outbreakmedicine.medical_specialtyAcademicSubjects/MED00910Coronavirus disease 2019 (COVID-19)medicine.medical_treatmentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)pandemicsNOPandemicResearch LettermedicinehumansThyroid cancerThyroid NeoplasmLS7_4Thyroid Neoplasms; Thyroidectomy; SARS-CoV-2; COVID-19; Pandemics; ItalyPandemicbusiness.industrySARS-CoV-2thyroid neoplasmsThyroidectomyCOVID-19Retrospective cohort studymedicine.diseaseComorbidityCOVID-19; comorbidity; humans; Italy; retrospective studies; SARS-CoV-2; thyroid neoplasms; pandemics; thyroidectomySettore MED/18 - Chirurgia Generalecomorbidityretrospective studiesItalyEmergency medicinethyroidectomyThyroidectomySurgeryAcademicSubjects/MED00010business
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