0000000000539063
AUTHOR
F. Haddad
Very high specific activity erbium 169Er production for potential receptor-targeted radiotherapy
Erbium 169Er is one of the most interesting radiolanthanides for new potential receptor-targeted β− therapy applications due to its low energy β− emissions, very low intensity ɣ rays and the possibility to use 68Ga or 44Sc as companion for diagnostic in a theranostics approach. Currently it can be produced in reactors through the neutron activation of highly enriched 168Er. The low specific activity of the produced carrier-added 169Er is limiting its use for receptor-targeted therapy. Nonetheless it is used for radiosynoviorthesis of small joints. The aim of this work is to develop a new large-scale production method for the supply of very high specific activity 169Er. Highly enriched 168Er…
MELISSA: Laser ion source setup at CERN-MEDICIS facility. Blueprint
The Resonance Ionization Laser Ion Source (RILIS) has become an essential feature of many radioactive ion beam facilities worldwide since it offers an unmatched combination of efficiency and selectivity in the production of ion beams of many different chemical elements. In 2019, the laser ion source setup MELISSA is going to be established at the CERN-MEDICIS facility, based on the experience of the workgroup LARISSA of the University Mainz and CERN ISOLDE RILIS team. The purpose is to enhance the capability of the radioactive ion beam supply for end users by optimizing the yield and the purity of the final product. In this article, the blueprint of the laser ion source, as well as the key …