0000000000539132

AUTHOR

Jean-emmanuel Kahn

showing 2 related works from this author

Efficacy of Azacitidine (AZA) in Autoimmune and Inflammatory Disorders (AID) Associated with Myelodysplastic Syndromes (MDS) and Chronic Myelomonocyt…

2015

Abstract Background: AID are seen in 10-30% of MDS and CMML. After initial response to steroids, AID are often poorly controlled and steroid-sparing drugs are difficult to use due to the underlying MDS/CMML. Some case reports suggest a beneficial role of AZA treatment in AID associated to MDS/CMML. Methods: We retrospectively analyzed 22 MDS/CMML patients (pts) with AID who received AZA in French centers between January 2007 and May 2014. Results: Median age of the 22 pts was 70y (range 41-84), including 6F/16M. Diagnosis of MDS/CMML preceded AID (n=8) by a median of 17 months (mo), was concomitant with (n=7) or followed AID (n=7) by a median of 20 mo. 14 pts had lower risk IPSS and 8 highe…

[ SDV ] Life Sciences [q-bio]business.industryMyelodysplastic syndromes[SDV]Life Sciences [q-bio]ImmunologyAzacitidineChronic myelomonocytic leukemiaCell BiologyHematologymedicine.diseaseBiochemistryInappropriate sinus tachycardia3. Good healthSierra leonePolymyalgia rheumatica[SDV] Life Sciences [q-bio]Mineralocorticoid receptorImmunologymedicinebusinessRelapsing polychondritismedicine.drug
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Systematic retrospective study of 64 patients with anti-Mi2 dermatomyositis: A classic skin rash with a necrotizing myositis and high risk of maligna…

2020

AdultMalemedicine.medical_specialtyRisk of malignancyMEDLINEDermatologyRisk AssessmentDermatomyositisNecrosisRisk FactorsNeoplasmsmedicineHumansMuscle SkeletalAgedAutoantibodiesRetrospective StudiesSkinbusiness.industryIncidenceNecrotizing myositisRetrospective cohort studyExanthemaMiddle AgedDermatomyositisPrognosismedicine.diseaseDermatologyRashFemalemedicine.symptombusinessMi-2 Nucleosome Remodeling and Deacetylase ComplexJournal of the American Academy of Dermatology
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