0000000000541173

AUTHOR

Antonio Prinzi

showing 2 related works from this author

<p>Circulating Irisin Levels as a Marker of Osteosarcopenic-Obesity in Cushing’s Disease</p>

2020

Purpose To evaluate circulating irisin levels in patients with active and controlled Cushing's disease (CD). Design Forty-four patients with CD evaluated during the active phase and after 12 months of biochemical remission and 40 controls were recruited. Methods Phenotypic, anthropometric, hormonal and metabolic parameters, including insulin sensitivity estimation by homeostatic model of insulin resistance, Matsuda index and oral disposition index and circulating irisin levels were evaluated. Results Patients with active CD showed lower irisin levels compared to controls (p<0.001) and controlled CD (p<0.001). The independent variables significantly associated with irisin were waist circumf…

Pharmacologymedicine.medical_specialtyWaistbusiness.industryOsteoporosisCushing's diseasemedicine.diseaseBody fat percentageObesityEndocrinologyInsulin resistanceInternal medicineInternal MedicinemedicinebusinessHomeostasisHormoneDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy
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Circulating Irisin Levels as a Marker of Osteosarcopenic-Obesity in Cushing’s Disease

2020

Purpose: To evaluate circulating irisin levels in patients with active and controlled Cushing’s disease (CD). Design: Forty-four patients with CD evaluated during the active phase and after 12 months of biochemical remission and 40 controls were recruited. Methods: Phenotypic, anthropometric, hormonal and metabolic parameters, including insulin sensitivity estimation by homeostatic model of insulin resistance, Matsuda index and oral disposition index and circulating irisin levels were evaluated. Results: Patients with active CD showed lower irisin levels compared to controls (p&lt;0.001) and controlled CD (p&lt;0.001). The independent variables significantly associated with irisin were wais…

irisin osteoporosis myopathy Cushing’s diseaseCushing’s diseaseirisinosteoporosisSettore MED/13 - EndocrinologiaOriginal ResearchmyopathyDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy
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