0000000000542004
AUTHOR
B. Fernandez
showing 6 related works from this author
Resonance State inH7
2007
The existence of the $^{7}\mathrm{H}$ nuclear system was investigated via a one-proton transfer reaction with a $^{8}\mathrm{He}$ beam at $15.4\mathrm{A}\text{ }\text{ }\mathrm{MeV}$ and a $^{12}\mathrm{C}$ gas target. The experimental setup was based on the active-target MAYA which allowed a complete reconstruction of the reaction kinematics. The existence of the $^{7}\mathrm{H}$ was confirmed with the identification of seven events where the system was formed with a resonance energy of ${0.57}_{\ensuremath{-}0.21}^{+0.42}\text{ }\text{ }\mathrm{MeV}$ above the $^{3}\mathrm{H}+4n$ threshold and a resonance width of ${0.09}_{\ensuremath{-}0.06}^{+0.94}\text{ }\text{ }\mathrm{MeV}$. This stu…
Production and Characterization of the $^{7}$H Resonance
2006
Détecteur MAYA; International audience; The 7H resonance was produced via one-proton transfer reaction between a 8He beam at 15.4A MeV and a 12C gas target. The experimental setup was based on the active-target MAYA which allowed a complete reconstruction of the reaction kinematics. The characterization of the identified 7H events resulted in a resonance energy of 600 keV above the 3H+4n threshold and a resonance width of 100 keV. This study represents the first unambiguous proof of the existence of the 7H state.
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
2014
Activating mutations in genes encoding phosphatidylinositol 3-kinase (PI3K)-AKT pathway components cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH, OMIM 603387)(1-3). Here we report that individuals with MPPH lacking upstream PI3K-AKT pathway mutations carry de novo mutations in CCND2 (encoding cyclin D2) that are clustered around a residue that can be phosphorylated by glycogen synthase kinase 313 (GSK-3 beta)(4). Mutant CCND2 was resistant to proteasomal degradation in vitro compared to wild-type CCND2. The PI3K-AKT pathway modulates GSK-3 beta activity(4), and cells from individuals with PIK3CA, PIK3R2 or AKT3 mutations showed similar CCND2 accumulation. CCND…
CCDC 672521: Experimental Crystal Structure Determination
2008
Related Article: S.Fustero, B.Fernandez, J.F.Sanz-Cervera, N.Mateu, S.Mosulen, R.J.Carbajo, A.Pineda-Lucena, C.R.de Arellano|2007|J.Org.Chem.|72|8716|doi:10.1021/jo701484w
CCDC 711699: Experimental Crystal Structure Determination
2010
Related Article: S.Fustero, P.Bello, B.Fernandez, C.del Pozo, G.B.Hammond|2009|J.Org.Chem.|74|7690|doi:10.1021/jo9013436
CCDC 672520: Experimental Crystal Structure Determination
2008
Related Article: S.Fustero, B.Fernandez, J.F.Sanz-Cervera, N.Mateu, S.Mosulen, R.J.Carbajo, A.Pineda-Lucena, C.R.de Arellano|2007|J.Org.Chem.|72|8716|doi:10.1021/jo701484w