0000000000542532

AUTHOR

De-an Guo

showing 2 related works from this author

Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.

2012

Abstract Background and aims GP-TCM is the 1st EU-funded Coordination Action consortium dedicated to traditional Chinese medicine (TCM) research. This paper aims to summarise the objectives, structure and activities of the consortium and introduces the position of the consortium regarding good practice, priorities, challenges and opportunities in TCM research. Serving as the introductory paper for the GP-TCM Journal of Ethnopharmacology special issue, this paper describes the roadmap of this special issue and reports how the main outputs of the ten GP-TCM work packages are integrated, and have led to consortium-wide conclusions. Materials and methods Literature studies, opinion polls and di…

medicine.medical_specialtyBiomedical ResearchCollaborative networkMEDLINEAlternative medicineAcupuncture TherapyOmicsGuidelines as TopicGuidelines03 medical and health sciencesPharmacovigilance0302 clinical medicineTraditional Chinese medicineDrug Discoverymedicinemedia_common.cataloged_instanceHumansEuropean UnionEuropean unionCooperative BehaviorMedicine Chinese Traditional030304 developmental biologyGrand Challengesmedia_commonGP-TCMPharmacology0303 health sciencesIntegrative MedicineEvidence-Based MedicineTraditional medicinebusiness.industrySystems BiologyAcupunctureEvidence-based medicineGenomics3. Good health030220 oncology & carcinogenesisEngineering ethicsIntersectoral CollaborationIntegrative medicineChinese herbal medicinebusinessDrugs Chinese HerbalPhytotherapyJournal of ethnopharmacology
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Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseases

2020

Abstract Adaptogens comprise a category of herbal medicinal and nutritional products promoting adaptability, resilience, and survival of living organisms in stress. The aim of this review was to summarize the growing knowledge about common adaptogenic plants used in various traditional medical systems (TMS) and conventional medicine and to provide a modern rationale for their use in the treatment of stress‐induced and aging‐related disorders. Adaptogens have pharmacologically pleiotropic effects on the neuroendocrine‐immune system, which explain their traditional use for the treatment of a wide range of conditions. They exhibit a biphasic dose‐effect response: at low doses they function as …

Premature agingAgingmedia_common.quotation_subjectmedicine.medical_treatmentReview ArticleAdaptabilitystress03 medical and health sciences0302 clinical medicineNetwork pharmacologyDrug DiscoveryAdaptogennetwork pharmacologyHumansMedicineethnopharmacologyResilience (network)Review Articles030304 developmental biologymedia_commonMedical systemsPharmacology0303 health sciencesPlant Extractsbusiness.industry3. Good healthadaptogenRisk analysis (engineering)030220 oncology & carcinogenesisMolecular MedicineTraditional UsebusinessSignal TransductionSystems pharmacologyMedicinal Research Reviews
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