0000000000542607

AUTHOR

Gemma Navarro

showing 2 related works from this author

Web Support for weight-loss interventions: PREDIRCAM2 clinical trial baseline characteristics and preliminary results

2018

An ongoing clinical trial is testing the efficacy of web telematic support in a structured program for obesity treatment and diabetes prevention. Participants were recruited from two tertiary-care hospitals and randomized to receive either a telematic intervention (TI) supported by PREDIRCAM2 web platform or a non-telematic intervention (NTI). All receive 1-year follow-up. Both interventions consist of tailored dietary and exercise prescriptions, based on a Mediterranean dietary pattern and general WHO exercise recommendations for adults. At 6 months, both groups have received 7 contacts, 3 exclusively telematic for the TI group. This is a preliminary result intention-to-treat analysis. One…

AdultMaleLifestyle modificationmedicine.medical_specialtyTelemedicine020205 medical informaticsMedicinaEndocrinology Diabetes and Metabolism02 engineering and technologyDiet MediterraneanBody Mass Index03 medical and health sciences0302 clinical medicineEndocrinologyLifestyle modificationDiabetes mellitusWeight Loss0202 electrical engineering electronic engineering information engineeringmedicineHumans030212 general & internal medicineHealthy LifestyleObesityExercise2. Zero hungerTelecomunicacionesbusiness.industryMiddle Agedmedicine.diseaseObesityMetabolic syndromeTelemedicine3. Good healthClinical trialMedical Laboratory TechnologyTreatment OutcomeWeight loss interventionsBaseline characteristicsPhysical therapyFemaleElectrónicaMetabolic syndromebusiness
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Detection, Analysis, and Quantification of GPCR Homo- and Heteroreceptor Complexes in Specific Neuronal Cell Populations Using the In Situ Proximity …

2018

GPCR’s receptosome operates via coordinated changes between the receptor expression, their modifications and interactions between each other. Perturbation in specific heteroreceptor complexes and/or their balance/equilibrium with other heteroreceptor complexes and corresponding homoreceptor complexes is considered to have a role in pathogenic mechanisms. Such mechanisms lead to mental and neurological diseases, including drug addiction, depression, Parkinson’s disease, and schizophrenia. To understand the associations of GPCRs and to unravel the global picture of their receptor–receptor interactions in the brain, different experimental detection techniques for receptor–receptor interactions…

0301 basic medicineIn situIn situ proximity ligation assayChemistryCellProximity ligation assayHeteroreceptorSettore BIO/09 - FisiologiaImmunohistochemistryReceptor–receptor interactionStoichiometryNOG protein-coupled receptors Immunohistochemistry In situ proximity ligation assay Heteroreceptor complexes Dimerization Receptor–receptor interaction Stoichiometry03 medical and health sciences030104 developmental biology0302 clinical medicinemedicine.anatomical_structureG protein-coupled receptorsBiophysicsmedicineHeteroreceptor complexesDimerization030217 neurology & neurosurgeryG protein-coupled receptor
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