0000000000544381

AUTHOR

Serpa Neto A

showing 2 related works from this author

Kinetics of plasma biomarkers of inflammation and lung injury in surgical patients with or without postoperative pulmonary complications

2017

Background Postoperative pulmonary complications (PPCs) are common after major abdominal surgery. The kinetics of plasma biomarkers could improve identification of patients developing PPCs, but the kinetics may depend on intraoperative ventilator settings. Objective To test whether the kinetics of plasma biomarkers are capable of identifying patients who will develop PPCs, and whether the kinetics depend on the intraoperative level of positive end-expiratory pressure (PEEP). Design A preplanned substudy of a randomised controlled trial. Setting Operation room of five centres. Patients Two hundred and forty-two adult patients scheduled for abdominal surgery at risk of developing PPCs. Interv…

AdultMalemedicine.medical_specialtyInflammationLung injuryGastroenterologyArticlelaw.inventionPositive-Pressure Respiration03 medical and health sciencesPostoperative Complications0302 clinical medicineRandomized controlled trial030202 anesthesiologylawInternal medicinemedicineHumansInflammationLungReceiver operating characteristicbusiness.industryLung InjuryAnesthesiology and Pain Medicinemedicine.anatomical_structure030228 respiratory systemAnesthesiaAdult; Biomarkers; Female; Humans; Inflammation; Inflammation Mediators; Lung Injury; Male; Positive-Pressure Respiration; Postoperative Complications; Anesthesiology and Pain MedicineBiomarker (medicine)FemaleInflammation Mediatorsmedicine.symptombusinessBiomarkersAbdominal surgeryBlood samplingEuropean Journal of Anaesthesiology
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Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications:LAS VEGAS - An observationa…

2017

BACKGROUND Limited information exists about the epidemiology and outcome of surgical patients at increased risk of postoperative pulmonary complications (PPCs), and how intraoperative ventilation was managed in these patients. OBJECTIVES To determine the incidence of surgical patients at increased risk of PPCs, and to compare the intraoperative ventilation management and postoperative outcomes with patients at low risk of PPCs. DESIGN This was a prospective international 1-week observational study using the ‘Assess Respiratory Risk in Surgical Patients in Catalonia risk score’ (ARISCAT score) for PPC for risk stratification. PATIENTS AND SETTING Adult patients requiring intraoperative venti…

MalePediatricsInternationalityRESPIRATORY-DISTRESS-SYNDROME0302 clinical medicinePostoperative Complications030202 anesthesiologyRisk FactorsEpidemiologyABDOMINAL-SURGERY80 and overMedicine and Health SciencesGeneral anaesthesiaAnesthesiaEND-EXPIRATORY-PRESSUREBERLIN DEFINITION030212 general & internal medicineProspective StudiesProspective cohort studyLungAged 80 and overFramingham Risk ScoreIncidence (epidemiology)RespirationMiddle AgedTreatment OutcomeArtificialFemalePRACTICE PATTERNSHumanmedicine.medical_specialtymechanical ventilation ; prospective observational study ; Intensive careAnesthesia GeneralNONCARDIOTHORACIC SURGERYNOAged; Aged 80 and over; Anesthesia General; Cross-Sectional Studies; Female; Humans; Intraoperative Care; Lung; Male; Middle Aged; Postoperative Complications; Prospective Studies; Respiration Disorders; Respiration Artificial; Risk Factors; Tidal Volume; Treatment Outcome; Internationality; Anesthesiology and Pain MedicineACUTE LUNG INJURY03 medical and health sciencesGENERAL-ANESTHESIAInternal medicinemedicineJournal ArticleTidal VolumeHumansMED/41 - ANESTESIOLOGIAGeneralAgedCross-Sectional StudieIntraoperative Carebusiness.industryRisk FactorRespiration DisorderRespiration DisordersRespiration ArtificialConfidence intervalPROTECTIVE MECHANICAL VENTILATIONProspective StudieAnesthesiology and Pain MedicineCross-Sectional StudiesRelative riskMAJOR NONCARDIAC SURGERYPostoperative ComplicationbusinessAbdominal surgery
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