0000000000544937
AUTHOR
Jun-beom Park
showing 3 related works from this author
The use of hydrogels in bone-tissue engineering
2010
Many different types of scaffold materials have been used for tissue engineering applications, and hydrogels form one group of materials that have been used in a wide variety of applications. Hydrogels are hydrophilic polymer networks and they represent an important class of biomaterials in biotechnology and medicine because many hydrogels exhibit excellent biocompatibility with minimal inflammatory responses and tissue damage. Many studies have demonstrated the use of hydrogels in bone-tissue engineering applications. In this report, the summary was conducted on various kinds of polymers and different modification methods of hydrogels to enhance bone formation. The results revealed that hy…
The use of simvastatin in bone regeneration
2009
Simvastatin is a chemical modification of lovastatin, a rate-limiting enzyme of the cholesterol synthesis pathway.Simvastatin has been reported to promote osteoblastic activity and inhibit osteoclastic activity. It is also reported to have an anti-inflammatory effect that works by decreasing the production of interleukin-6 and interleukin-8.The successful use of simvastatin to promote bone formation in vivo depends on the local concentration, and there have been continuous efforts to find an appropriate delivery system. Different doses produce different effects and doses should be prescribed with caution considering benefits and risks. There have been many studies demonstrating the bone-pro…
Use of mineral trioxide aggregrate in the non-surgical repair of perforating invasive cervical resorption
2008
Mineral trioxide aggregate (MTA) has shown potential as a repair material for perforations. This clinical case demonstrates that when MTA was used as a repair material for root perforation due to invasive cervical resorption, the tooth was well in function for 27 months. Both clinical and radiographic follow-up showed a stable condition without any probing defect, ongoing root resorption, or apical pathosis.