0000000000546401

AUTHOR

P. Tamaro

GERM CELL TUMOURS IN CHILDREN- A Report of 84 Cases

In January 1991 a Protocol for diagnosis and treatment of Germ Cell Tumours (GCT) in children was activated in 15 Italian Paediatric Centres.

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Mature and immature teratoma: A report from the second Italian pediatric study

Background. Teratomas demonstrate a benign clinical behavior, however they may recur with malignant components or as teratoma, and in a small group of patients prognosis could be fatal. After the ®rst Italian study, we collected cases of teratoma, alongside the protocol for malignant germ cell tumors. Procedure. Patients with teratoma were collected from 2004 to 2014. Teratomas were classi®ed according to the WHO classi®cations, as mature and immature. Patients with pathological aFP and/or bHCG, and those with a malignant germ cell component were not included. Results. The study enrolled 219 patients (150 mature, 69 immature teratomas) with a median age at diagnosis of 42 months. The primar…

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TUMORI A CELLULE GERMINALI IN ETA' PEDIATRICA. RISULTATI DEL PROTOCOLLO AIEOP "TG-91".

Gli Autori riportano i risultati del Protocollo AIEOP-91 presentando igli 88 casi registrati in 15 Centro AIEOP dal gGennaio 1991 al Dicembre 193

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TUMORI A CELLULE GERMINALI MALIGNI IN ETA’ PEDIATRICA: RISULTATI DEL II STUDIO COOPERATIVO ITALIANO TCG 98

Gli Autori presentano i risultati del Secondo Studio Cooperativo Italiano sui Tumori a Cellulle Germinali Maligni del bambino, esito del Proytocollo Nazionale TCG 98.

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TERATOMA IMMATURO EXTRACRANICO: Risultati dello Studio Cooperativo AIEOP "TCG-91".

I Teratomi Immatuti sono tumori costituiti da tessuto non maligno ma con potenzialità evolutiva maligna. Gli Autori presentano i dati dello Studio Cooperativo "TCG-91".

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Teratoma with a malignant somatic component in pediatric patients: The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) experience

BACKGROUND: Teratoma with a malignant somatic component (TMSC) is rare but described in adults, whereas information on pediatric presentation is sparse. PROCEDURE: The Associazione Italiana Ematologia Oncologia Pediatrica identified 14 cases of TMSC. Clinical files and pathology specimens were reviewed. RESULTS: The series (9 female, 5 male) showed the following disease: testis (2), sacrococcygeal (3), ovary (3), retroperitoneum (3), mediastinum (2), and foot soft tissue (1). Distribution of the somatic component was: carcinoma (4), pancreatic neuroendocrine tumor (1), neuroblastoma (3), rhabdomyosarcoma (3), rhabdomyosarcoma plus liposarcoma, chondrosarcoma, neurogenic sarcoma (1), chondro…

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