0000000000548668
AUTHOR
Anne Garnier
An Estimate of Global, Regional and Seasonal Cirrus Cloud Radiative Effects Contributed by Homogeneous Ice Nucleation
There are two fundamental mechanisms through which cirrus clouds form; homo- and heterogeneous ice nucleation (henceforth hom and het). The relative contribution of each mechanism to ice crystal production often determines the microphysical and radiative properties of a cirrus cloud. This study attempts to estimate the radiative contribution of hom relative to het by constraining the cloud microphysics in a climate model to conform with satellite retrievals of cirrus cloud effective diameter De, where the sampled cirrus cloud base had a temperature T Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation) satellite retrievals for cirrus clouds are compared against an updat…
Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
AIMS: The optic atrophy 1 (OPA1) protein is an essential protein involved in the fusion of the mitochondrial inner membrane. Despite its high level of expression, the role of OPA1 in the heart is largely unknown. We investigated the role of this protein in Opa1(+/-) mice, having a 50% reduction in OPA1 protein expression in cardiac tissue. METHODS AND RESULTS: In mutant mice, cardiac function assessed by echocardiography was not significantly different from that of the Opa1(+/+). Electron and fluorescence microscopy revealed altered morphology of the Opa1(+/-) mice mitochondrial network; unexpectedly, mitochondria were larger with the presence of clusters of fused mitochondria and altered c…