0000000000551800
AUTHOR
William Smith
Efficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.
BACKGROUND Degludec is an ultralong-Acting, once-daily basal insulin that is approved for use in adults, adolescents, and children with diabetes. Previous open-label studies have shown lower day-To-day variability in the glucose-lowering effect and lower rates of hypoglycemia among patients who received degludec than among those who received basal insulin glargine. However, data are lacking on the cardiovascular safety of degludec. METHODS We randomly assigned 7637 patients with type 2 diabetes to receive either insulin degludec (3818 patients) or insulin glargine U100 (3819 patients) once daily between dinner and bedtime in a double-blind, treat-To-Target, event-driven cardiovascular outco…
Environmentally sensitive behaviours and capercaillie (Tetrao urogallus) conservation in the Cairngorms National Park
Since the 1970s local capercaillie (Tetrao urogallus) populations have been in severe decline in Scotland from over 20,000 individuals to just over 1200, 80% of which are confined to the Spey Valley in the Cairngorms National Park. This decline is thought to be due to a number of factors such as climate change, habitat loss and fragmentation. However, these issues are further compounded by increasing disturbance from human activity. In recent years, tourism and outdoor recreation have risen dramatically in the Cairngorms National Park leading to potentially increased disturbance events. For this reason it is important to understand the social dynamics that surround capercaillie conservation…