0000000000552182

AUTHOR

Jonathan Wilson

showing 4 related works from this author

Efficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.

2017

BACKGROUND Degludec is an ultralong-Acting, once-daily basal insulin that is approved for use in adults, adolescents, and children with diabetes. Previous open-label studies have shown lower day-To-day variability in the glucose-lowering effect and lower rates of hypoglycemia among patients who received degludec than among those who received basal insulin glargine. However, data are lacking on the cardiovascular safety of degludec. METHODS We randomly assigned 7637 patients with type 2 diabetes to receive either insulin degludec (3818 patients) or insulin glargine U100 (3819 patients) once daily between dinner and bedtime in a double-blind, treat-To-Target, event-driven cardiovascular outco…

Insulin degludecBlood GlucoseMalemedicine.medical_treatmentDEVOTE Study GroupInsulin GlargineType 2 diabetesKaplan-Meier Estimate030204 cardiovascular system & hematologylaw.inventiondiabetes ; insulin0302 clinical medicineRandomized controlled triallawCardiovascular DiseaseGLUCOSE CONTROL11 Medical and Health SciencesRISKCOMPLICATIONSOUTCOMESIncidenceGeneral MedicineMiddle AgedInsulin Long-ActingVARIABILITYCardiovascular Diseasesdiabetes mellitusFemaleLife Sciences & BiomedicineHumanmedicine.drugmedicine.medical_specialty030209 endocrinology & metabolismAged; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus Type 2; Double-Blind Method; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Incidence; Insulin Glargine; Insulin Long-Acting; Kaplan-Meier Estimate; Male; Middle Aged; Medicine (all)HypoglycemiaBedtimeArticleEVENTS03 medical and health sciencesHYPOGLYCEMIAMedicine General & InternalDouble-Blind MethodInternal medicineDiabetes mellitusGeneral & Internal MedicinemedicineHumansHypoglycemic AgentsIntensive care medicineMETAANALYSISAgedScience & TechnologyHypoglycemic AgentInsulin glarginebusiness.industryInsulinmedicine.diseaseDiabetes Mellitus Type 2businessBASAL INSULIN
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Tevatron Run II combination of the effective leptonic electroweak mixing angle

2018

The Ministry of Science and Innovation and the Consolider-Ingenio 2010 Program and the European Union community Marie Curie Fellowship Contract No. 302103.

Drell-Yan processsemianalytical programsPhysics and Astronomy (miscellaneous)FERMION PAIR PRODUCTIONUPGRADETevatronhadron-colliders01 natural sciencesHigh Energy Physics - ExperimentPhysics Particles & Fieldselectron: pair productionHigh Energy Physics - Experiment (hep-ex)MONTE-CARLOUNIVERSAL MONTE-CARLOELECTROMAGNETIC CALORIMETERDZERO[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]HADRON COLLIDERSangular distributionBatavia TEVATRON CollMonte CarloPhysicsscattering [anti-p p]gauge bosonPhysicsElectroweak interactionDrell–Yan processWeinberg anglespontaneous symmetry breaking [electroweak interaction]muon: pair productionPhysical Sciencesmixing angle [electroweak interaction]bosonPHOTOSmass: measured [W]asymmetryParticle physicsFOS: Physical sciencesSEMIANALYTICAL PROGRAMddc:500.2Astronomy & Astrophysicselectroweak interaction: spontaneous symmetry breaking114 Physical sciences530programmingW: mass: measuredStandard Modelanti-p p: colliding beams[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex]hadroproduction [Z0]0103 physical sciencesanti-p p: scatteringddc:530High Energy Physicspair production [electron]pair production [muon]CALORIMETER010306 general physicsQED RADIATIVE-CORRECTIONSQed radiative-corrections; fermion pair production; universal; Monte Carlo; parton distributions; hadron-colliders; electromagnetic; calorimeter;semianalytical programs; E(+)E(-) annihilation; boson; production; D0 detectorGauge bosonBOSON PRODUCTIONMuonScience & Technologyelectroweak interaction: mixing angleAnti-p p: scattering | anti-p p: colliding beams | Z0: hadroproduction | Z0: leptonic decay | electroweak interaction: spontaneous symmetry breaking | electroweak interaction: mixing angle | muon: pair production | W: mass: measured | Weinberg angle | Batavia TEVATRON Coll | angular distribution | electron: pair production | Drell-Yan process | gauge boson | programming | asymmetry | CDF | DZERO | experimental resultsIDENTIFICATION010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyuniversalWeinberg angleZ0: hadroproductionQED RADIATIVE-CORRECTIONS; FERMION PAIR PRODUCTION; UNIVERSAL; MONTE-CARLO; PARTON DISTRIBUTIONS; HADRON COLLIDERS; ELECTROMAGNETIC; CALORIMETER; SEMIANALYTICAL PROGRAM; E(+)E(-) ANNIHILATION; BOSON; PRODUCTION; D0 DETECTORleptonic decay [Z0]E(+)E(-) ANNIHILATIONelectromagneticPARTON DISTRIBUTIONSExperimental High Energy PhysicsZ0: leptonic decayD0 DETECTORCDFHigh Energy Physics::Experimentproductioncolliding beams [anti-p p]Leptonexperimental results
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Combined Forward-Backward Asymmetry Measurements in Top-Antitop Quark Production at the Tevatron

2018

The CDF and D0 experiments at the Fermilab Tevatron have measured the asymmetry between yields of forward- and backward-produced top and antitop quarks based on their rapidity difference and the asymmetry between their decay leptons. These measurements use the full data sets collected in proton-antiproton collisions at a center-of-mass energy of √s=1.96  TeV. We report the results of combinations of the inclusive asymmetries and their differential dependencies on relevant kinematic quantities. The combined inclusive asymmetry is At¯tFB=0.128±0.025. The combined inclusive and differential asymmetries are consistent with recent standard model predictions.

Top quarkTevatronGeneral Physics and Astronomypair production [top]01 natural sciences7. Clean energyHigh Energy Physics - ExperimentSubatomär fysikHigh Energy Physics - Experiment (hep-ex)DZEROSubatomic Physicsddc:550[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Quantum ChromodynamicsBatavia TEVATRON CollGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)media_commonPhysicsscattering [anti-p p]Particle properties02 Physical Sciencesrapidity: differenceCDF; Tevatron; top-quarkPhysicsdifference [rapidity]asymmetry [angular distribution]kinematicsPhysical Sciencestop: pair productionQuarkParticle physicsGeneral Physicsangular distribution: asymmetryTevatron Collidermedia_common.quotation_subjectPhysics MultidisciplinaryFOS: Physical sciencesForward backwardddc:500.2Hadron-hadron interactionsAsymmetryComputer Science::Digital Libraries114 Physical sciencesMarie curieCDF Collaborationanti-p p: colliding beamsPhysics and Astronomy (all)[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex]0103 physical sciencesanti-p p: scatteringmedia_common.cataloged_instanceddc:530High Energy PhysicsEuropean union010306 general physicsScience & Technology1960 GeV-cms010308 nuclear & particles physicshep-exHigh Energy Physics::PhenomenologyTop quarkQ007TFBResearch councilExperimental High Energy PhysicsCDFHigh Energy Physics::Experimentcolliding beams [anti-p p]High Energy Physics Top quark Hadron-hadron interactions Quantum Chromodynamics Particle properties Tevatron ColliderD0 Collaborationexperimental resultsPhysical Review Letters
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Interleukin 10 polymorphisms in ankylosing spondylitis.

2003

Genetic polymorphisms of the IL10 promoter region have been implicated in many autoimmune diseases, including seronegative spondyloarthropathies. We studied three SNPs (IL10-1087, -824, and -597) and two microsatellites (IL10R and IL10G) lying within the promoter region of IL10 for association with susceptibility to and clinical manifestations of ankylosing spondylitis (AS), a common form of spondyloarthritis. Four hundred and sixty-eight individuals from 182 Finnish families affected with AS were studied. No association between individual IL10 promoter region polymorphisms or marker haplotype was observed with susceptibility to AS, but weak association was noted between the IL10-597 and -8…

musculoskeletal diseasesImmunologychemical and pharmacologic phenomenaSingle-nucleotide polymorphismBiologyPolymorphism Single Nucleotideimmune system diseasesparasitic diseasesGeneticsmedicineSNPHumansSpondylitis AnkylosingAlleleSpondylitisGenetics (clinical)AllelesGenetic associationGeneticsAnkylosing spondylitisPolymorphism GeneticHaplotypehemic and immune systemsmedicine.diseaseInterleukin-10ImmunologyBASFIMicrosatellite Repeats
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