0000000000555748

AUTHOR

Andrea Liberato

showing 8 related works from this author

Pb2+complexes of small-cavity azamacrocyclic ligands: thermodynamic and kinetic studies

2017

The synthesis, acid-base behavior and Pb2+ coordination chemistry of the new aza-scorpiand like ligand 5-[2-(N-2-fluorenyl)ethylamino]-2,5,8-triaza[9]-2,6-pyridinophane (L1) have been studied by potentiometry, NMR and spectrofluorimetric titrations, and the results are compared with those obtained for the related compounds L2, lacking the fluorenyl group, and L3, the macrocycle lacking the pendant arm. The crystal structures obtained for complexes [PbL1][PbL1Cl](NO3)Cl2·4H2O (1) and [PbL3](ClO4)2 (2) reveal that the metal ion is located over the plane defined by the nitrogen atoms of the macrocyclic core due to its inability to accommodate the large Pb2+ ion in the macrocyclic cavity. For L…

0301 basic medicinechemistry.chemical_classification030102 biochemistry & molecular biologyStereochemistryLigandMetal ions in aqueous solutionCrystal structure010402 general chemistry01 natural sciencesDissociation (chemistry)0104 chemical sciencesCoordination complexIonInorganic ChemistryMetal03 medical and health sciencesCrystallographychemistryvisual_artvisual_art.visual_art_mediumLone pairDalton Transactions
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Methylation as an effective way to generate SOD-activity in copper complexes of scorpiand-like azamacrocyclic receptors

2018

Abstract Methylation of the secondary amine groups of a scorpiand-type ligand consisting of a pyridine spacer connected through methylene groups to a tris(2-aminomethyl) unit with the pendant arm further functionalised with a 3-pyridine unit leads to a ligand whose Cu(II) complex exhibits threefold enhanced SOD activity with respect to the non-methylated ligand. Potentiometric studies indicate the formation of [CuL] 2+ species with a stability three orders of magnitude lower than that formed with the related non-methylated ligand. Kinetic studies indicate that methylation of the secondary nitrogens causes a deceleration of both the complex formation and the acid-induced dissociation of the …

Tris010405 organic chemistryChemistryPotentiometric titration010402 general chemistryPhotochemistry01 natural sciencesMedicinal chemistryRedoxDissociation (chemistry)0104 chemical sciencesInorganic ChemistryMetalchemistry.chemical_compoundvisual_artPyridineMaterials Chemistryvisual_art.visual_art_mediumAmine gas treatingPhysical and Theoretical ChemistryMethyleneInorganica Chimica Acta
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Coordination Chemistry of Cu2+ Complexes of Small N-Alkylated Tetra-azacyclophanes with SOD Activity

2018

A new tetraaza-pyridinophane macrocycle (L1) N-alkylated with two isopropyl and one methyl groups symmetrically disposed has been prepared and its behavior compared with those of the unsubstituted pyridinophane (L3) and the related compound with three methyl groups (L2). The protonation studies show that, first, a proton binds to the central methylated amine group of L1, while, second protonation leads to a reorganization of the protons that are at this stage attached to the lateral isopropylated amines. The X-ray structure of [HL1]+ agrees with the UV–vis and NMR studies as well as with the results of DFT calculations. The stability of the Cu2+ complexes decreases on increasing the bulkine…

chemistry.chemical_classification010405 organic chemistryLigandProtonationCrystal structureAlkylation010402 general chemistry01 natural sciencesMedicinal chemistrySquare pyramidal molecular geometry0104 chemical sciencesCoordination complexInorganic ChemistrychemistryPhysical and Theoretical ChemistryIsopropylAlkylInorganic Chemistry
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CCDC 1559249: Experimental Crystal Structure Determination

2017

Related Article: Aida Nebot-Guinot, Andrea Liberato, M. Angeles Máñez, M. Paz Clares, Antonio Doménech, Javier Pitarch-Jarque, Alvaro Martínez-Camarena, Manuel G. Basallote, Enrique García-España|2018|Inorg.Chim.Acta|472|139|doi:10.1016/j.ica.2017.08.044

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters39-dimethyl-6-{2-[methyl(pyridinium-3-ylmethyl)ammonio]ethyl}-615-diaza-39-diazoniabicyclo[9.3.1]pentadeca-1(15)1113-triene tetrakis(perchlorate) hydrateExperimental 3D Coordinates
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CCDC 1559236: Experimental Crystal Structure Determination

2017

Related Article: Aida Nebot-Guinot, Andrea Liberato, M. Angeles Máñez, M. Paz Clares, Antonio Doménech, Javier Pitarch-Jarque, Alvaro Martínez-Camarena, Manuel G. Basallote, Enrique García-España|2018|Inorg.Chim.Acta|472|139|doi:10.1016/j.ica.2017.08.044

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(mu-2-[39-dimethyl-36915-tetraazabicyclo[9.3.1]pentadeca-1(15)1113-trien-6-yl]-N-methyl-N-[(pyridin-3-yl)methyl]ethan-1-amine)-(mu-2-[39-dimethyl-36915-tetraazabicyclo[9.3.1]pentadeca-1(15)1113-trien-6-yl]-N-methyl-N-[(pyridin-3-yl)methyl]ethan-1-aminium)-di-copper(ii) pentakis(perchlorate) monohydrate
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CCDC 1827335: Experimental Crystal Structure Determination

2018

Related Article: Álvaro Martínez-Camarena, Andrea Liberato, Estefanía Delgado-Pinar, Andrés G. Algarra, Javier Pitarch-Jarque, José M. Llinares, M. Ángeles Mañez, Antonio Domenech-Carbó, Manuel G. Basallote, Enrique García-España|2018|Inorg.Chem.|57|10961|doi:10.1021/acs.inorgchem.8b01492

chloro-[6-methyl-39-bis(propan-2-yl)-36915-tetraazabicyclo[9.3.1]pentadeca-1(15)1113-triene]-copper(ii) perchlorateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1827337: Experimental Crystal Structure Determination

2018

Related Article: Álvaro Martínez-Camarena, Andrea Liberato, Estefanía Delgado-Pinar, Andrés G. Algarra, Javier Pitarch-Jarque, José M. Llinares, M. Ángeles Mañez, Antonio Domenech-Carbó, Manuel G. Basallote, Enrique García-España|2018|Inorg.Chem.|57|10961|doi:10.1021/acs.inorgchem.8b01492

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parametersaqua-[6-methyl-39-bis(propan-2-yl)-36915-tetraazabicyclo[9.3.1]pentadeca-1(15)1113-triene]-copper(ii) bis(perchlorate) monohydrateExperimental 3D Coordinates
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CCDC 1827336: Experimental Crystal Structure Determination

2018

Related Article: Álvaro Martínez-Camarena, Andrea Liberato, Estefanía Delgado-Pinar, Andrés G. Algarra, Javier Pitarch-Jarque, José M. Llinares, M. Ángeles Mañez, Antonio Domenech-Carbó, Manuel G. Basallote, Enrique García-España|2018|Inorg.Chem.|57|10961|doi:10.1021/acs.inorgchem.8b01492

6-methyl-39-bis(propan-2-yl)-36915-tetraazabicyclo[9.3.1]pentadeca-1(15)1113-trien-6-ium perchlorate hemihydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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