0000000000557528

AUTHOR

Ana-lídia-soares Cota

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Virulence of Streptococcus mutans: An intrafamilial cohort study on transmission of genotypes

2020

Background The main aims of this cohort study were to measure the intrafamilial risk of transmission, sharing and stability of the most virulent S. mutans genotypes. Material and Methods A total of 392 clinical isolates of S. mutans obtained from caries-active adults and genotyped to evaluate their transmissibility over time. After extraction of the chromosomal DNA, PCR were performed to detect the genes involved in the production of GbpA (gbpA) and mutacin types I, II, III and IV (mutAI, mutAII, mutAIII and mutAIV). Results The gbpA, mutAI, mutAII, mutAIII and mutAIV genes were detected in 77.3, 12.5, 51, 16.6 and 89.8% of S. mutans isolates, respectively. The virulence of S. mutans was as…

0301 basic medicineOral Medicine and PathologyResearchVirulence030206 dentistryBiologybiology.organism_classificationIntrafamilial transmission:CIENCIAS MÉDICAS [UNESCO]Streptococcus mutansMicrobiology03 medical and health sciences030104 developmental biology0302 clinical medicineGenotypeUNESCO::CIENCIAS MÉDICASChromosomal dnaColonizationGeneGeneral DentistryCohort studyJournal of Clinical and Experimental Dentistry
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