0000000000558749

AUTHOR

Lombardo F

Results from a prospective observational study of men with premature ejaculation treated with dapoxetine or alternative care: The PAUSE study

Abstract Background Dapoxetine hydrochloride is a selective serotonin reuptake inhibitor and the first drug approved for the on-demand treatment of premature ejaculation (PE). Its safety was established in a thorough clinical development program. Objective To characterize the safety profile of dapoxetine in PE treatment and to report the incidence, severity, and type of adverse events. Design, setting, and participants We conducted a 12-wk, open-label, observational study with a 4-wk, postobservational contact. A total of 10 028 patients were enrolled, with 6712 patients (67.6%) treated with dapoxetine 30–60mg (group A)and 3316 (32.4%) treated with alternative care/nondapoxetine (group B). …

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Interventional treatment of sialoliths in main salivary glands

Purpose. The aim of our study was to demonstrate the effectiveness of interventional radiology in the treatment of sialolithiasis, as the first-choice treatment for the removal of stones located in the middle and proximal tracts of the main salivary ducts, and to assess its limitations and contraindications. Material and methods. Between February 1998 and May 2001 eleven interventional removals of sialoliths were performed for recurrent obstruction of the main salivary duct associated with chronic sialadenitis. Patients were selected on the basis of a preliminary sialogram, designed to determine the location and size of the stone. Exclusion criteria were location of the stone in the gland h…

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Schwannoma of the larynx. Case report

Neuretogenous tumours of the larynx are extremely uncommon. We present a case of schwannoma of the larynx and review pertinent data in the literature. Laryngeal schwannoma was discovered in a 80-year-old woman who complained of persistent dysphonia. The histological findings leading to diagnosis together with the therapeutic surgical procedure are described. There was no postoperative complication and functional outcome was excellent at six months follow-up, demonstrating that conservative surgery is required for this type of disease. Conservative surgery provides excellent results. Although very rare, schwannoma should be taken into consideration in the differential diagnosis of any laryng…

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Survey of neonatal respiratory care and surfactant administration in very preterm infants in the Italian neonatal network

INTRODUCTION: Variation of respiratory care is described between centers around the world. The Italian Neonatal Network (INN), as a national group of the Vermont-Oxford Network (VON) allows to perform a wide analysis of respiratory care in very low birth weight infants. METHODS: We analyzed the dataset of infants enrolled in the INN in 2009 and 2010 and, for surfactant administration only, from 2006 to 2010 from 83 participating centers. All definitions are those of the (VON). A questionnaire analysis was also performed with a questionnaire on centers practices. RESULTS: We report data for 8297 infants. Data on ventilator practices and outcomes are outlined. Variation for both practices and…

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