0000000000560270

AUTHOR

Justus Pankok

showing 3 related works from this author

Effects of moclobemide on sexual performance and nocturnal erections in psychogenic erectile dysfunction

2001

Rationale and objectives: We tested the hypothesis that the selective reversible MAO-A inhibitor moclobemide has a specific therapeutic effect on erectile dysfunction independent of its antidepressive properties. Methods: In a double-blind placebo controlled study, 12 male outpatients suffering from psychogenic erectile dysfunction without any other psychiatric disorder were investigated. Based on comprehensive diagnosis before the beginning of the study, organic factors relevant for sexual function were excluded. The treatment period was 8 weeks. Half the patients received 450 mg moclobemide during the first week, and 600 mg afterwards; the others received placebo. Apart from assessment of…

AdultMalemedicine.medical_specialtyMonoamine Oxidase InhibitorsMoclobemidePlacebo-controlled studyPlaceboDouble-Blind MethodErectile DysfunctionInternal medicineMoclobemidemedicineHumansPsychogenic diseasePharmacologyAnalysis of VariancePenile ErectionTherapeutic effectElectroencephalographyMiddle Agedmedicine.diseaseSurgeryErectile dysfunctionClinical Global ImpressionPsychologySexual functionmedicine.drugPsychopharmacology
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Temporal relationship between nocturnal erections and rapid eye movement episodes in healthy men.

2003

The exact temporal relationship between spontaneous nocturnal erections and rapid eye movement (REM) sleep was studied in healthy men with the aim of creating a basis for a more sophisticated analysis of nocturnal erection measurements in physiological research and clinical applications. The vast majority of erectile events was coupled to REM episodes, where the latency between the beginning of erections and REM episodes showed a large variability. Moreover, a correlation analysis revealed a highly significant decrease of the latency over the course of the night. The time variant properties of the coupling between erections and REM sleep point to more complex dynamics of the central control…

AdultMalemedicine.medical_specialtymedia_common.quotation_subjectPolysomnographyRapid eye movement sleepSleep REMPolysomnographyNocturnalPhysical medicine and rehabilitationInternal medicinemedicineReaction TimeHumansBiological Psychiatrymedia_commonmedicine.diagnostic_testmusculoskeletal neural and ocular physiologyPenile ErectionEye movementElectroencephalographyMiddle Agedmedicine.diseaseCircadian RhythmPsychiatry and Mental healthNeuropsychology and Physiological PsychologyPsychophysiologyEndocrinologyErectile dysfunctionCorrelation analysisPsychologycirculatory and respiratory physiologyVigilance (psychology)PsychophysiologyNeuropsychobiology
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Sleep investigations in erectile dysfunction

2003

Abstract Regarding the aetiology of erectile dysfunction, beside numerous organic causes in many cases psychological factors play an important role. The pathophysiological mechanisms underlying the so-called psychogenic erectile dysfunction are not yet understood. Based on a neurobiological approach to psychogenic erectile dysfunction, polysomnographic investigations were carried out with the aim of identifying possible alterations of the sleep EEG. 24 male patients with psychogenic erectile dysfunction without detectable organic factors or other mental disorders were studied in the sleep laboratory, as well as an age-matched control group without sexual dysfunctions. Beside a reduction of …

AdultMaleSleep Wake DisordersSleep StagesPolysomnographyRapid eye movement sleepElectroencephalographyMiddle AgedBioinformaticsmedicine.diseaseSleep in non-human animalsPsychiatry and Mental healthSexual dysfunctionErectile dysfunctionErectile DysfunctionmedicineHumansPsychogenic diseasemedicine.symptomSleepPsychologyNeuroscienceBiological PsychiatryDepression (differential diagnoses)Slow-wave sleepJournal of Psychiatric Research
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