0000000000563655

AUTHOR

Edurne Carbonell

showing 1 related works from this author

SARS-CoV-2 RNA load in the lower respiratory tract, viral RNAemia and N-antigenemia in critically ill adult COVID-19 patients: relationship with biom…

2021

ABSTRACTBackgroundLittle is known about the comparative kinetics of SARS-CoV-RNA load in the lower respiratory tract and in blood compartment in patients admitted to the intensive care unit, and how these relate to biomarkers of COVID-19 severity.MethodsSeventy-three consecutive critically ill COVID-19 patients (median age, 65 years) were recruited. Serial lower respiratory tract (n=165) and plasma (n=340) specimens were collected. RT-PCR and lateral flow immunochromatography assay were used for SARS-CoV-2 RNA quantitation and N protein detection in plasma, respectively. Serum levels of inflammatory and tissue-damage biomarkers in paired specimens were analyzed.ResultsSARS-CoV-RNA was detec…

medicine.medical_specialtybiologyCoronavirus disease 2019 (COVID-19)business.industryCritically illSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)RNAIntensive care unitGastroenterologylaw.inventionFerritinmedicine.anatomical_structureDisease severitylawInternal medicinebiology.proteinMedicinebusinessRespiratory tract
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