0000000000564236

AUTHOR

M Carmen Gómez-mateo

showing 2 related works from this author

mRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival

2017

// Ana-Barbara Garcia-Garcia 1, 2, * , M. Carmen Gomez-Mateo 3, 7, * , Rebeca Hilario 2 , Pilar Rentero-Garrido 2 , Alvaro Martinez-Domenech 4 , Veronica Gonzalez-Albert 2 , Andres Cervantes 5 , Pablo Marin-Garcia 6 , Felipe Javier Chaves 1, 2 , Antonio Ferrandez-Izquierdo 3 and Luis Sabater 4 1 CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM), Madrid, Spain 2 Unidad de Genomica y Diagnostico Genetico. Fundacion Investigacion Clinico de Valencia, Instituto de Investigacion Sanitaria Clinico de Valencia (INCLIVA), Valencia, Spain 3 Department of Pathology, Faculty of Medicine and Odontology, University of Valencia and Clinical Hospital of Valencia, and Instituto de Investigacio…

0301 basic medicinemedicine.medical_specialtyMrna expressionpancreatic ductal adenocarcinomaBioinformatics03 medical and health sciences0302 clinical medicinepatient survivalmicrodissected cellsPancreatic cancerMedicineStage (cooking)ValenciaLymph nodeSurvival analysisGynecologyregional lymph node metastasesbiologybusiness.industryCancerPatient survivalmedicine.diseasebiology.organism_classification030104 developmental biologymedicine.anatomical_structureOncology030220 oncology & carcinogenesisgene expressionbusinessResearch PaperOncotarget
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Ki-67 immunoexpression and radiological assessment of necrosis improves accuracy of conventional and modified core biopsy systems in predicting the f…

2021

Based on the French Federation Nationale des Centers de Lutte Contre le Cancer (FNCLCC) grading system, this study assesses the accuracy of conventional and modified core biopsy (CB) systems in predicting the final grade (low vs high) assigned to the resected specimen. Substituting Ki-67 immunoexpression for mitotic count, and radiological for histological assessment of necrosis, we used two modified FNCLCC CB grading systems: (1) Ki-67 immunoexpression alone, and (2) Ki-67 plus radiological assessment of necrosis. We graded 199 soft tissue sarcomas (STS) from nine centers, and compared the results for the conventional (obtained from local histopathology reports) and modified CB systems wit…

AdultMalemedicine.medical_specialtySoft Tissue NeoplasmsPathology and Forensic MedicineRadiological necrosisNecrosisCore biopsymedicineBiomarkers TumorHumansGrading (education)Retrospective StudiesNot evaluatedReceiver operating characteristicbiologybusiness.industrySarcomasSoft tissueSarcomaCell Biologymedicine.diseaseKi-67 AntigenRadiological weaponKi-67biology.proteinKi-67HistopathologyFemaleSarcomaBiopsy Large-Core NeedleNuclear medicinebusinessFNCLCC grading system
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