0000000000568291

AUTHOR

S. Ng

showing 7 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Search for intermediate mass black hole binaries in the first and second observing runs of the Advanced LIGO and Virgo network

2019

Gravitational wave astronomy has been firmly established with the detection of gravitational waves from the merger of ten stellar mass binary black holes and a neutron star binary. This paper reports on the all-sky search for gravitational waves from intermediate mass black hole binaries in the first and second observing runs of the Advanced LIGO and Virgo network. The search uses three independent algorithms: two based on matched filtering of the data with waveform templates of gravitational wave signals from compact binaries, and a third, model-independent algorithm that employs no signal model for the incoming signal. No intermediate mass black hole binary event was detected in this sear…

binary: massneutron star: binaryAstronomybinary: angular momentumAstrophysicsdetector: network01 natural sciencesGeneral Relativity and Quantum CosmologyPhysics Particles & FieldsLIMITSclustersLIGOgravitational waveGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)QCQBastro-ph.HEPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Settore FIS/01black hole: spinPhysicsintermediate mass black hole binarieNumerical relativityGeneral relativitygravitational wavesgravitational waves; intermediate mass black hole binaries; Advanced LIGO and VirgoPhysical Sciences[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]Astrophysics - High Energy Astrophysical PhenomenastarsGeneral relativitygr-qcAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesalternative theories of gravitySTARS; CLUSTERS; LIMITSAstrophysics::Cosmology and Extragalactic AstrophysicsGeneral Relativity and Quantum Cosmology (gr-qc)Astronomy & Astrophysicsgravitational radiation: direct detectionGeneral Relativity and Quantum CosmologySettore FIS/05 - Astronomia e AstrofisicaBinary black hole0103 physical sciencesddc:530010306 general physicsAstrophysics::Galaxy AstrophysicsSTFCScience & Technology010308 nuclear & particles physicsGravitational waveAdvanced LIGO and Virgointermediate mass black hole binariesRCUKGravitational Wave Physicsblack hole: massMass ratiobinary: compact04.80.NnLIGOgravitational radiation detectorNeutron starVIRGOblack hole: binaryIntermediate-mass black holerelativity theorygravitational radiation: emission95.55.Ymmass ratioDewey Decimal Classification::500 | Naturwissenschaften::530 | Physik07.05.Kflimits[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]CLUSTERSSTARSGravitational waves Black holes (astronomy) Gravitational self force
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Surgeons' fear of getting infected by COVID19: A global survey

2020

During the last three months, COVID- 19 pandemic had led to a serious backlog of operations globally, and plans for restarting operation are imperative. Recommendations for surgical activities were studied, aiming to protect the surgical staff from being infected. In the meantime, it is also important to give attention to the surgeon’s personal feeling during work. We conducted a survey to investigate global surgi- cal practices during the COVID-19 pandemic, and the surgeon’s personal feeling was also investigated in the sur- vey. In this special letter, we performed multivariate analysis to explore factors that associated with surgeon’s fear of getting infected by COVID-19.

Surgery COVID-19medicine.medical_specialty2019-20 coronavirus outbreakInfectious Disease Transmission Patient-to-Professionalsurvey covid19Coronavirus disease 2019 (COVID-19)Attitude of Health PersonnelSettore MED/18 - CHIRURGIA GENERALESevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Infectious Disease TransmissionCOVID-19. Global surgery.MEDLINEGlobal HealthNOPatient-to-ProfessionalTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]Surveys and QuestionnairesCorrespondencemedicineGlobal healthInfection controlHumansGeneralPersonal protective equipmentPersonal Protective EquipmentLS7_4SurgeonsInfection Controlcovid-19; pandemic; surgerySARS-CoV-2business.industrypandemicVaccinationCOVID-19covidFearSettore MED/18Occupational DiseasesCOVID-19; Global Health; Humans; Infection Control; Occupational Diseases; Personal Protective Equipment; Surgeons; Surveys and Questionnaires; Attitude of Health Personnel; Fear; Infectious Disease Transmission Patient-to-ProfessionalSurgeon - infection - COVID19 - surveyFamily medicineSurgerybusiness
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Impact of asymptomatic COVID-19 patients in global surgical practice during the COVID-19 pandemic

2020

The rapid spread of COVID-19 has changed the global surgical care. Patients infected with COVID-19 may present without typical symptoms, and such asymptomatic patients may potentially trigger in-hospital outbreaks by transmitting the disease to health care providers and other hospitalized patients. Further, asymptomatic COVID-19 patients have worse postop- erative outcomes with an unexpectedly high morbidity and mortality, reaching 20⋅5 per cent deaths. However, we do not have objective global data on this issue. In an attempt to clarify the current global surgical practice under the COVID-19 pandemic particularly focusing on the preoperative screening of asymptomatic COVID-19 patients, we …

2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)covid-19 pandemic surgerySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Settore MED/18 - CHIRURGIA GENERALEMEDLINECOVID-19. Global surgery.AsymptomaticCOVID-19 Critical Pathways Cross Infection Cross-Sectional Studies Health Care Surveys Humans Pandemics Postoperative Complications SARS-CoV-2 Surgical Procedures Operative Asymptomatic InfectionsCOVID-19; Critical Pathways; Cross Infection; Cross-Sectional Studies; Health Care Surveys; Humans; Pandemics; Postoperative Complications; SARS-CoV-2; Surgical Procedures Operative; Asymptomatic InfectionsNOsurgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]Postoperative ComplicationsPandemicCorrespondencemedicineHumansPandemicsAsymptomatic InfectionsLS7_4COVIDCross InfectionSurgical ProceduresCritical pathwaysbusiness.industrySARS-CoV-2pandemicCOVID-19Surgical proceduresOperativeSettore MED/18covid 19 surgical practiceCOVID-19 - surgeryCross-Sectional StudiesSurgical Procedures OperativeHealth Care SurveysEmergency medicineCritical Pathwaysmedicine.symptombusiness
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Search for Gravitational-wave Signals Associated with Gamma-Ray Bursts during the Second Observing Run of Advanced LIGO and Advanced Virgo

2019

We present the results of targeted searches for gravitational-wave transients associated with gamma-ray bursts during the second observing run of Advanced LIGO and Advanced Virgo, which took place from 2016 November to 2017 August. We have analyzed 98 gamma-ray bursts using an unmodeled search method that searches for generic transient gravitational waves and 42 with a modeled search method that targets compact-binary mergers as progenitors of short gamma-ray bursts. Both methods clearly detect the previously reported binary merger signal GW170817, with p-values of <9.38 10-6 (modeled) and 3.1 10-4 (unmodeled). We do not find any significant evidence for gravitational-wave signals associate…

Burst astrophysicAstrofísicaneutron star: binary010504 meteorology & atmospheric sciencesBinary numberAstrophysics01 natural sciencesLIGOQCSUPERNOVArelativistic jetsQBHigh Energy Astrophysical Phenomena (astro-ph.HE)Settore FIS/01counterpartGRBGravitational waves (678)Physical SciencesRELATIVISTIC JETSAstrophysics - High Energy Astrophysical PhenomenaGravitational waveGravitationstarsblack-holeAstrophysics::High Energy Astrophysical PhenomenaGeneral Relativity and Quantum Cosmology (gr-qc)precursor activityGravitational wavesSettore FIS/05 - Astronomia e AstrofisicasupernovaCORE-COLLAPSEGamma-ray burstGravitational wave sourcesScience & TechnologyVirgoRCUKAstronomy and AstrophysicsHigh energy astrophysics (739)RedshiftDewey Decimal Classification::500 | Naturwissenschaften::520 | Astronomie Kartographiedetector: sensitivityVIRGOSpace and Planetary Sciencegravitational radiation: emissionBLACK-HOLEddc:520Gravitational wave astronomyGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]STARSGravitacióAstronomySignalGeneral Relativity and Quantum CosmologyBurst astrophysicslocalizationemission010303 astronomy & astrophysicsPhysicsDetectorGamma-ray bursts (629)[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]Gravitational wave sourcePRECURSOR ACTIVITYGamma-ray burstsLIGO (920)High energy astrophysicsdata analysis methodBurst astrophysics (187)FOS: Physical sciencesAstrophysics::Cosmology and Extragalactic Astrophysicsgamma ray: burstAstronomy & AstrophysicsMASSgravitational radiation: direct detectionGravitational wave astronomy Gravitational wave sources LIGO; Gravitational waves Gamma-ray bursts Burst astrophysics High energy astrophysicsGravitational wave astronomy (675)electromagnetic field: production0103 physical sciencesnumerical calculationsGRB; gravitational waves; LIGO; VirgoSTFC0105 earth and related environmental sciencesgravitational wavesneutron starsGravitational waveCOUNTERPARTgravitational radiationLIGOcore-collapsegravitational radiation detectorGravitational wave sources (677)radiationNeutron starPhysics and AstronomymassRADIATIONEMISSIONGravitational wave astronomy; Gravitational wave sources; LIGO; Gravitational waves; Gamma-ray bursts; Burst astrophysics; High energy astrophysics
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A Fermi Gamma-Ray Burst Monitor Search for Electromagnetic Signals Coincident with Gravitational-wave Candidates in Advanced LIGO's First Observing R…

2019

We present a search for prompt gamma-ray counterparts to compact binary coalescence gravitational wave (GW) candidates from Advanced LIGO's first observing run (O1). As demonstrated by the multimessenger observations of GW170817/GRB 170817A, electromagnetic and GW observations provide complementary information about the astrophysical source and, in the case of weaker candidates, may strengthen the case for an astrophysical origin. Here we investigate low-significance GW candidates from the O1 compact-binary coalescence searches using the Fermi Gamma-ray Burst Monitor (GBM), leveraging its all-sky and broad energy coverage. Candidates are ranked and compared to background to measure signific…

AstrofísicaGravitacióAstronomyAstrophysics::High Energy Astrophysical Phenomenagamma-ray burst: generalFOS: Physical sciencesAstrophysicsAstronomy & Astrophysicsgeneral [gamma-ray burst]01 natural sciencesCoincidenceCoincident0103 physical sciences010306 general physics010303 astronomy & astrophysicsgravitational waveSTFCQCQBHigh Energy Astrophysical Phenomena (astro-ph.HE)Settore FIS/01Physicsastro-ph.HEScience & TechnologySolar flareGravitational wavegamma-ray burst: general; gravitational waves; Astronomy and Astrophysics; Space and Planetary ScienceRCUKAstronomy and AstrophysicsAstronomy and AstrophysicLIGOPhysics and Astronomygravitational wavesSpace and Planetary SciencePhysical Sciencesgamma-ray burst: general; gravitational wavesgeneral; gravitational waves; Astronomy and Astrophysics; Space and Planetary Science [gamma-ray burst]False alarmAstrophysics - High Energy Astrophysical PhenomenaGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Fermi Gamma-ray Space Telescope
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Search for GW signals associated with GRBs

2021

We present the results of targeted searches for gravitational-wave transients associated with gamma-ray bursts during the second observing run of Advanced LIGO and Advanced Virgo, which took place from 2016 November to 2017 August. We have analyzed 98 gamma-ray bursts using an unmodeled search method that searches for generic transient gravitational waves and 42 with a modeled search method that targets compact-binary mergers as progenitors of short gamma-ray bursts. Both methods clearly detect the previously reported binary merger signal GW170817, with p-values of <9.38x10^-6^ (modeled) and 3.1x10^-4^ (unmodeled). We do not find any significant evidence for gravitational-wave signals assoc…

Astrophysics and AstronomyGamma-ray astronomyhigh energy astrophysicsAstrophysics::High Energy Astrophysical PhenomenaPhysicsAstrophysics::Cosmology and Extragalactic Astrophysicsstellar astronomyGamma ray burstsGravitational wavesCosmologyobservational astronomyGamma ray astronomyGamma-ray burstsAstrophysical ProcessesNatural Sciences
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