0000000000569249

AUTHOR

T. Pham

showing 8 related works from this author

LBA-5 Phase Ib study of the anti-TIGIT antibody tiragolumab in combination with atezolizumab in patients with metastatic esophageal cancer

2021

OncologyTIGITbiologyAtezolizumabbusiness.industryCancer researchbiology.proteinMedicineIn patientHematologyAntibodybusinessMetastatic esophageal cancerAnnals of Oncology
researchProduct

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
researchProduct

Performance of the upgraded PreProcessor of the ATLAS Level-1 Calorimeter Trigger

2020

The PreProcessor of the ATLAS Level-1 Calorimeter Trigger prepares the analogue trigger signals sent from the ATLAS calorimeters by digitising, synchronising, and calibrating them to reconstruct transverse energy deposits, which are then used in further processing to identify event features. During the first long shutdown of the LHC from 2013 to 2014, the central components of the PreProcessor, the Multichip Modules, were replaced by upgraded versions that feature modern ADC and FPGA technology to ensure optimal performance in the high pile-up environment of LHC Run 2. This paper describes the features of the newMultichip Modules along with the improvements to the signal processing achieved.

Physics - Instrumentation and Detectors:Kjerne- og elementærpartikkelfysikk: 431 [VDP]Computer sciencePhysics::Instrumentation and Detectors01 natural sciencesHigh Energy Physics - Experiment030218 nuclear medicine & medical imaginglaw.inventionSubatomär fysikHigh Energy Physics - Experiment (hep-ex)0302 clinical medicinelawSubatomic Physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]PreprocessorDetectors and Experimental Techniquesphysics.ins-detInstrumentationMathematical PhysicsFPGASettore FIS/01Signal processingLarge Hadron ColliderInstrumentation and Detectors (physics.ins-det)trigger [calorimeter]ATLASCalorimeters; Trigger concepts and systems (hardware and software)Calorimetermedicine.anatomical_structure:Nuclear and elementary particle physics: 431 [VDP]Trigger concepts and systems (hardware and software)design [electronics]Particle Physics - ExperimentComputer hardwareperformanceCiências Naturais::Ciências Físicas530 Physics:Ciências Físicas [Ciências Naturais]Analog-to-digital converterFOS: Physical sciences61003 medical and health sciencesCalorimetersAtlas (anatomy)0103 physical sciencesmedicineHigh Energy Physicsddc:610[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Field-programmable gate arraysignal processingCalorimeterScience & Technologyhep-ex010308 nuclear & particles physicsbusiness.industrycalorimeter: trigger530 Physikcalibrationanalog-to-digital converterpile-upExperimental High Energy Physicselectronics: readoutbusinessreadout [electronics]Energy (signal processing)electronics: design
researchProduct

Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (Intensive Care M…

2018

The members of the LUNG SAFE Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for this error.

Critical Care and Intensive Care Medicine
researchProduct

Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study

2018

Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initial…

MaleARDSmedicine.medical_treatmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]ARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS;Critical Care and Intensive Care Medicineassisted ventilation0302 clinical medicineRisk Factors030212 general & internal medicinerisk factor AdultTidal volumecomparative studyeducation.field_of_studyRespiratory Distress SyndromeMortality rateRemission Inductiontidal volumeARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS; Critical Care and Intensive Care MedicineARDS reassessmentartificial ventilationclinical trialimmunosuppressive treatmentadult respiratory distress syndromeMiddle AgedARDS SurvivalMonte Carlo methodmedicine.anatomical_structureclassificationpositive end expiratory pressureCardiologyDisease ProgressionSOFA scoredisease severityFemaleAdultmedicine.medical_specialtyPopulationdisease classificationArticleNO03 medical and health sciencesremissionlength of stayAnesthesiologyInternal medicinemedicinepneumoniaSequential Organ Failure Assessment ScoreHumanshumaneducationAgedMechanical ventilationhospital mortalityLungbusiness.industryRisk Factordisease associationRespiratory Distress Syndrome AdultPersisting ARDSmedicine.diseasemajor clinical studymortalityRespiration Artificialbreathing rate030228 respiratory systemdisease exacerbationBerlin criteria ARDSbusinessIntensive care medicine
researchProduct

Observation and Measurement of Forward Proton Scattering in Association with Lepton Pairs Produced via the Photon Fusion Mechanism at ATLAS

2020

The observation of forward proton scattering in association with lepton pairs (eþe− þ p or μþμ− þ p) produced via photon fusion is presented. The scattered proton is detected by the ATLAS Forward Proton spectrometer, while the leptons are reconstructed by the central ATLAS detector. Proton-proton collision data recorded in 2017 at a center-of-mass energy of ffiffiffi s p ¼ 13 TeV are analyzed, corresponding to an integrated luminosity of 14.6 fb−1. A total of 57 (123) candidates in the ee þ p (μμ þ p) final state are selected, allowing the background-only hypothesis to be rejected with a significance exceeding 5 standard deviations in each channel. Proton-tagging techniques are introduced f…

:Kjerne- og elementærpartikkelfysikk: 431 [VDP]Photon13000 GeV-cmsLHC ATLASmeasured [channel cross section]General Physics and Astronomy01 natural sciences7. Clean energyHigh Energy Physics - Experimentelectron: pair productionSubatomär fysikHigh Energy Physics - Experiment (hep-ex)Integrated LuminosityFusion Mechanismphoton photon: fusionspectrometer [p]Subatomic Physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]scattering [p p]pair production [lepton]Electroweak interactionQuantum ChromodynamicsParticle productionNuclear ExperimentSettore FIS/01PhysicsQuantum chromodynamicsObservation and MeasurementQuantum electrodynamicsLarge Hadron Colliderp: spectrometerdimuonAtlas (topology)COLLISIONS; PHYSICS; GAMMA; LIGHT; LHCElectroweak interactionDetectorphotonATLASfusion [photon photon]muon: pair production:Nuclear and elementary particle physics: 431 [VDP]PhotoproductionLIGHTCERN LHC CollATLAS DetectorsLHCcolliding beams [p p]channel cross section: measuredParticle Physics - Experimentsmall-angleParticle physicsp p: scatteringCOLLISIONSp: particle identificationCiências Naturais::Ciências Físicas530 Physicslepton: pair production:Ciências Físicas [Ciências Naturais]Particles & FieldsFOS: Physical sciencesparticle identification [p]LHC ATLAS High Energy PhysicsPHYSICS0103 physical sciencesddc:530Cross-Section Measurementpair production [electron]pair production [muon]High Energy Physics010306 general physicsCiencias ExactasATLAS CollaborationScience & TechnologySpectrometerhep-exPomeronsFísicaGAMMALeptonsProton Scatteringexclusive productionPrecision measurementsProton Proton CollisionsStandard DeviationExperimental High Energy PhysicsElementary Particles and FieldsHigh Energy Physics::ExperimentHadron-hadron collisionsp p: colliding beamsLeptonacceptanceexperimental results
researchProduct

Measurement of photon?jet transverse momentum correlations in 5.02 TeV Pb + Pb and pp collisions with ATLAS

2019

Jets created in association with a photon can be used as a calibrated probe to study energy loss in the medium created in nuclear collisions. Measurements of the transverse momentum balance between isolated photons and inclusive jets are presented using integrated luminosities of 0.49 nb−1 of Pb + Pb collision data at TeV and 25 pb−1 of pp collision data at TeV recorded with the ATLAS detector at the LHC. Photons with transverse momentum GeV and are paired with all jets in the event that have GeV and pseudorapidity . The transverse momentum balance given by the jet-to-photon ratio, , is measured for pairs with azimuthal opening angle . Distributions of the per-photon jet yield as a function…

PhotonLEAD-LEAD COLLISIONS; PP COLLISIONS; ROOT-S(NN)=2.76 TEV; DEPENDENCEheavy ion: scatteringPhysics::Instrumentation and DetectorsMonte Carlo methodRelativistic heavy ion collisionsphoton–jet transverse momentum correlationsnucl-ex01 natural sciencesHigh Energy Physics - ExperimentDouble Drell–YanSubatomär fysikHigh Energy Physics - Experiment (hep-ex)Double parton-scatteringDEPENDENCESubatomic Physicsscattering [p p][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]luminositiesCollisions ROOT-S(NN)=2.76 TEVNuclear Experiment (nucl-ex)Nuclear Experimentdimension: 2GeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)Nuclear ExperimentMonte CarloComputingMilieux_MISCELLANEOUSQCComputer Science::DatabasesPhysicsJet (fluid)Large Hadron ColliderSettore FIS/01 - Fisica Sperimentalephotonyield [jet]transverse momentum: correlationATLASlcsh:QC1-999:Mathematics and natural scienses: 400::Physics: 430::Nuclear and elementary particle physics: 431 [VDP]medicine.anatomical_structureCERN LHC Coll2 [dimension]nuclear matterLHCLEAD-LEAD COLLISIONSjet: yieldParticle Physics - ExperimentNuclear and High Energy Physicsp p: scatteringenergy loss [parton]530 PhysicsCiências Naturais::Ciências FísicasAstrophysics::High Energy Astrophysical Phenomena:Ciências Físicas [Ciências Naturais]FOS: Physical sciencesddc:500.2LHC ATLAS High Energy Physics[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]jets Nuclear physicsAtlas (anatomy)0103 physical sciencesCalibrationmedicineddc:530RapidityNuclear Physics - Experiment5020 GeV-cms/nucleonHigh Energy Physics010306 general physicsCiencias ExactasFour-lepton productionHiggs golden decay channelPP COLLISIONSScience & Technology010308 nuclear & particles physicshep-exHigh Energy Physics::Phenomenologynucleus:Matematikk og naturvitenskap: 400::Fysikk: 430::Kjerne- og elementærpartikkelfysikk: 431 [VDP]FísicaNuclear mattercalibrationjet quenching* Automatic Keywords *rapidityExperimental High Energy PhysicsHigh Energy Physics::Experimentparton: energy losscorrelation [transverse momentum]lcsh:Physicsexperimental resultsPhysics Letters B
researchProduct

Erratum to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC‑GLOSSARI): a multicenter, multinational, 14-day inception coh…

2018

In both the original publication (DOI 10.1007/s00134-015-4206-2) and the first erratum (DOI 10.1007/s00134-016-4317-4), the members of the IC-GLOSSARI Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for these errors and is pleased to list the members of the groups here: (Table presented.).

Critical Care and Intensive Care Medicine
researchProduct