0000000000570566

AUTHOR

A. Santini

showing 3 related works from this author

Solution strategies for 1D elastic continuum with long-range interactions: Smooth and fractional decay

2010

Abstract An elastic continuum model with long-range forces is addressed in this study within the context of approximate analytical methods. Such a model stems from a mechanically-based approach to non-local theory where long-range central forces are introduced between non-adjacent volume elements. Specifically, long-range forces depend on the relative displacement, on the volume product between interacting elements and they are proportional to a proper, material-dependent, distance-decaying function. Smooth-decay functions lead to integro-differential governing equations whereas hypersingular, fractional-decay functions lead to a fractional differential governing equation of Marchaud type. …

Mechanical EngineeringMathematical analysisMODELSFinite differenceContext (language use)Finite difference coefficientFunction (mathematics)GRADIENT ELASTICITYCondensed Matter PhysicsBARFractional calculusRange (mathematics)NONLOCAL ELASTICITY; GRADIENT ELASTICITY; MODELS; BARNONLOCAL ELASTICITYCentral forceMechanics of MaterialsGeneral Materials ScienceGalerkin methodSettore ICAR/08 - Scienza Delle CostruzioniCivil and Structural EngineeringMathematics
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A Non-Local Two Dimensional Foundation Model

2012

Classical foundation models such as the Pasternak and the Reissner models have been recently reformulated within the framework of non-local mechanics, by using the gradient theory of elasticity. To contribute to the research effort in this field, this paper presents a two-dimensional foundation model built by using a mechanically based non-local elasticity theory, recently proposed by the authors. The foundation is thought of as an ensemble of soil column elements resting on an elastic base. It is assumed that each column element is acted upon by a local Winkler-like reaction force exerted by the elastic base, by contact shear forces and volume forces due, respectively, to adjacent and non-…

Mechanical EngineeringAttenuationLinear elasticityShear forceNon-local mechanicFinite difference methodSubgrade modelsMechanicsElasticity (physics)Foundation modelFractional calculuNon localFractional calculusReactionNon-local foundation Long-Range Interactions Fractional CalculusLinear elasticitySettore ICAR/08 - Scienza Delle CostruzioniMathematics
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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