0000000000571247

AUTHOR

K. Singh

showing 6 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Breeding annual legumes for sustainable agricultures must target for new and more complex variety ideotypes

2013

International audience; Although yield and total biomass produced by annual legumes remain major objectives for breeders, environment-friendly, resource use efficient including symbiotic performance, resilient production in the context of climate change, adaptation to sustainable cropping systems (reducing leaching and glasshouse gas emissions), adaptation to diverse uses (seeds for feeds foods, non-food, forage or green manures), and finally new ecological services such as pollinator protection, imply the development of innovative genotypes, definition of new ideotypes and acceptance of their commercialisation. Taken as a whole, this means more complex and integrated objectives for breeder…

sustainable agriculture[SDV.SA]Life Sciences [q-bio]/Agricultural sciences[SDV.SA] Life Sciences [q-bio]/Agricultural sciencesannual legumessustainable agriculturesbreedinglegumesvariety ideotypes[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SDV.BV] Life Sciences [q-bio]/Vegetal Biologyideotypes
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Search for a Lorentz-violating sidereal signal with atmospheric neutrinos in IceCube

2010

A search for sidereal modulation in the flux of atmospheric muon neutrinos in IceCube was performed. Such a signal could be an indication of Lorentz-violating physics. Neutrino oscillation models, derivable from extensions to the Standard Model, allow for neutrino oscillations that depend on the neutrino's direction of propagation. No such direction-dependent variation was found. A discrete Fourier transform method was used to constrain the Lorentz and CPT-violating coefficients in one of these models. Due to the unique high energy reach of IceCube, it was possible to improve constraints on certain Lorentz-violating oscillations by three orders of magnitude with respect to limits set by oth…

PhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Nuclear and High Energy PhysicsParticle physicsMuonSolar neutrinoAstrophysics::High Energy Astrophysical PhenomenaHigh Energy Physics::PhenomenologyFOS: Physical sciencesSolar neutrino problemHigh Energy Physics - ExperimentStandard ModelHigh Energy Physics - PhenomenologyHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)Sidereal timeMeasurements of neutrino speedddc:530High Energy Physics::ExperimentNeutrinoAstrophysics - High Energy Astrophysical PhenomenaNeutrino oscillation
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IceCube Sensitivity for Low-Energy Neutrinos from Nearby Supernovae ( Corrigendum )

2014

Keywords: neutrinos ; supernovae: general ; instrumentation: detectors ; errata ; addenda Reference EPFL-ARTICLE-198916doi:10.1051/0004-6361/201117810eView record in Web of Science Record created on 2014-05-19, modified on 2017-05-12

PhysicsSupernovaLow energyWeb of scienceSpace and Planetary Scienceddc:520Astronomy and AstrophysicsAstrophysicsInstrumentation (computer programming)Sensitivity (control systems)Neutrino
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Measurement of the atmospheric neutrino energy spectrum from 100 GeV to 400 TeV with IceCube

2010

A measurement of the atmospheric muon neutrino energy spectrum from 100 GeV to 400 TeV was performed using a data sample of about 18,000 up-going atmospheric muon neutrino events in IceCube. Boosted decision trees were used for event selection to reject mis-reconstructed atmospheric muons and obtain a sample of up-going muon neutrino events. Background contamination in the final event sample is less than one percent. This is the first measurement of atmospheric neutrinos up to 400 TeV, and is fundamental to understanding the impact of this neutrino background on astrophysical neutrino observations with IceCube. The measured spectrum is consistent with predictions for the atmospheric muon ne…

Nuclear and High Energy PhysicsParticle physicsPhysics::Instrumentation and DetectorsSolar neutrinoAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesDeep IceSouth-PoleHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)ddc:530Muon neutrinoNeutrino oscillationPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)FluxHigh Energy Physics::PhenomenologyOptical-PropertiesDetectorSolar neutrino problemHigh Energy Physics - PhenomenologyNeutrino detectorMeasurements of neutrino speedPhysics::Accelerator PhysicsHigh Energy Physics::ExperimentNeutrino astronomyNeutrinoAstrophysics - High Energy Astrophysical PhenomenaTelescopesPhys.Rev.D
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Collectivity in the light radon nuclei measured directly via Coulomb excitation

2015

Background: Shape coexistence in heavy nuclei poses a strong challenge to state-of-the-art nuclear models, where several competing shape minima are found close to the ground state. A classic region for investigating this phenomenon is in the region around Z=82 and the neutron midshell at N=104. Purpose: Evidence for shape coexistence has been inferred from α-decay measurements, laser spectroscopy, and in-beam measurements. While the latter allow the pattern of excited states and rotational band structures to be mapped out, a detailed understanding of shape coexistence can only come from measurements of electromagnetic matrix elements. Method: Secondary, radioactive ion beams of Rn202 and Rn…

Nuclear and High Energy Physics[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]PopulationFOS: Physical sciencesCoulomb excitationshape coexistence01 natural sciences0103 physical sciencesNuclear Physics - ExperimentNeutroncollectivityNuclear Experiment (nucl-ex)010306 general physicseducationSpectroscopyNuclear ExperimentPhysicseducation.field_of_studyta114010308 nuclear & particles physicsGamma rayradonPhysique atomique et nucléaire3. Good healthRadonExcited stateQuadrupoleAtomic physicsGround state
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