0000000000574029
AUTHOR
O. Baker
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…
Dark Sectors and New, Light, Weakly-Coupled Particles
Dark sectors, consisting of new, light, weakly-coupled particles that do not interact with the known strong, weak, or electromagnetic forces, are a particularly compelling possibility for new physics. Nature may contain numerous dark sectors, each with their own beautiful structure, distinct particles, and forces. This review summarizes the physics motivation for dark sectors and the exciting opportunities for experimental exploration. It is the summary of the Intensity Frontier subgroup "New, Light, Weakly-coupled Particles" of the Community Summer Study 2013 (Snowmass). We discuss axions, which solve the strong CP problem and are an excellent dark matter candidate, and their generalizatio…