0000000000577287

AUTHOR

P. Fransvea

showing 4 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
researchProduct

Emergency hernia repair in the elderly: multivariate analysis of morbidity and mortality from an Italian registry

2020

Abstract Purpose The incidence of inguinal hernia is higher in elderly because of aging-related diseases like prostatism, bronchitis, collagen laxity. A conservative management is common in elderly to reduce surgery-related risks, however watchful waiting can expose to obstruction and strangulation. The aim of the present study was to assess the impact of emergency surgery in a large series of elderly with complicated groin hernia and to identify the independent risk factors for postoperative morbidity and mortality. The predictive performance of prognostic risk scores has been also assessed. Methods This is a prospective observational study carried out between January 2017 and June 2018 in…

medicine.medical_specialtymedicine.medical_treatmentSettore MED/18 - CHIRURGIA GENERALENOPostoperative complicationsElderlyLaparotomymedicineHerniaIncarcerated herniabusiness.industryExplorative laparotomyGroin hernia · Incarcerated hernia · Elderly · Postoperative complications · Emergency surgery · Charlson’s comorbidity indexmedicine.diseaseHernia repairComorbiditySurgeryGroin herniaInguinal herniaCharlson’s comorbidity indexEmergency surgerySurgerybusinessWatchful waitingCharlson’s comorbidity index; Elderly; Emergency surgery; Groin hernia; Incarcerated hernia; Postoperative complicationsAbdominal surgery
researchProduct

Frailty and emergency surgery in the elderly: protocol of a prospective, multicenter study in Italy for evaluating perioperative outcome (The FRAILES…

2018

Improvements in living conditions and progress in medical management have resulted in better quality of life and longer life expectancy. Therefore, the number of older people undergoing surgery is increasing. Frailty is often described as a syndrome in aged patients where there is augmented vulnerability due to progressive loss of functional reserves. Studies suggest that frailty predisposes elderly to worsening outcome after surgery. Since emergency surgery is associated with higher mortality rates, it is paramount to have an accurate stratification of surgical risk in such patients. The aim of our study is to characterize the clinicopathological findings, management, and short-term outcom…

Elderly patient; Emergency surgery; Frailty; Geriatric; Risk assessment; Scores; Aged; Aged 80 and over; Clinical Protocols; Emergencies; Female; Frailty; Humans; Italy; Logistic Models; Male; Multivariate Analysis; Outcome Assessment Health Care; Postoperative Complications; Prognosis; Prospective Studies; ROC Curve; Risk Assessment; Frail ElderlyMaleOutcome Assessment030230 surgerylaw.invention0302 clinical medicinePostoperative ComplicationsQuality of lifeClinical ProtocolslawOutcome Assessment Health Care80 and overProspective StudiesProspective cohort studyMultivariate AnalysiAged 80 and overEmergencieFrailtyMortality rateScoreScoresPrognosisIntensive care unitElderly patient; Emergency surgery; Frailty; Geriatric; Risk assessment; Scores; Aged; Aged 80 and over; Clinical Protocols; Emergencies; Female; Frailty; Humans; Italy; Logistic Models; Male; Multivariate Analysis; Outcome Assessment (Health Care); Postoperative Complications; Prognosis; Prospective Studies; ROC Curve; Risk Assessment; Frail ElderlyItaly030220 oncology & carcinogenesiselderly patient emergency surgery frailty geriatric risk assessment scoresEmergency surgeryFemaleRisk assessmentElderly patientHumanmedicine.medical_specialtyElderly patient; Emergency surgery; Frailty; Geriatric; Risk assessment; Scores;Logistic ModelPrognosiFrail ElderlyRisk AssessmentNO03 medical and health sciencesOutcome Assessment (Health Care)medicineHumansClinical ProtocolAgedbusiness.industryPerioperativeElderly patient; Emergency surgery; Frailty; Geriatric; Risk assessment; ScoresSurgeryHealth CareProspective StudieSettore MED/18 - Chirurgia GeneraleLogistic ModelsROC CurveEmergency medicineMultivariate AnalysisLife expectancyObservational studySurgeryPostoperative ComplicationEmergenciesbusinessGeriatric
researchProduct

Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study

2021

Abstract Background The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted the surgical community. Recommendations have been published to manage patients needing surgery during the COVID-19 pandemic. This survey, under the aegis of the Italian Society of Endoscopic Surgery, aims to analyze how Italian surgeons have changed their practice during the pandemic. Methods The authors designed an online survey that was circulated for completion to the Italian departments of general surgery registered in the Italian Ministry of Health database in December 2020. Questions were divided into three sections: hospital organization, screening policies, and safety profile of…

Laparoscopic surgerySettore MED/18 - CHIRURGIA GENERALEmedicine.medical_treatmentlaparoscopyCOVID-19; Elective surgery; Emergency surgery; Laparoscopic surgery; SurveyOral HealthLaparoscopic surgerycross infection (MeSH)COVID-19; Elective surgery; Emergency surgery; Laparoscopic surgery; Survey.Surveys and QuestionnairesEpidemiologyPandemicInfection controlPractice Patterns Physicians'emergency surgeryLaparoscopySurveyhumansmedicine.diagnostic_testGeneral Commentarylaparoscopic surgeryinfection controlItalyEmergency surgeryphysicians'Original ArticleElective Surgical ProcedureHumanheating ventilation air conditioningmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)fallow periodelective surgical procedurespandemicsNOaerosol generating proceduresSurvey.COVID-19; elective surgery; emergency surgery; laparoscopic surgery; survey; COVID-19; elective surgical procedures; humans; infection control; Italy; laparoscopy; pandemics; practice patterns physicians'; SARS-CoV-2; surveys and questionnairesmedicinesurveyElective surgeryElective surgeryInfection ControlElective Surgical ProcedurePandemicbusiness.industrySARS-CoV-2General surgerySurvey; Laparoscopic surgery; COVID-19; Elective surgery; Emergency surgeryCOVID-19practice patternsSurgeryelective surgerysurveys and questionnairesLaparoscopySurgerybusiness
researchProduct