ChemInform Abstract: Nonporous Silica Microspheres in the Micron and Submicron Size Range: Manufacture, Characterization and Application

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

Nonporous Silica Microspheres in the Micron and Submicron Size Range

Uniform nonporous silica microspheres in the micrometer and submicrometer size range are formed by a process which involves reacting alkoxysilanes with water in a short chain alcohol using dissolved ammonia as a morphological catalyst.