0000000000579410

AUTHOR

S. Kaneko

showing 4 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
researchProduct

Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3)…

2022

It has come to our attention that the name of one of the authors in our manuscript was incorrectly spelled ‘Jinyoung Byan’; the correct spelling is ‘Jinyoung Byun’ as in the author list above. In addition, the excel files of the supplementary tables were not included during the online publication of our article. These have now been made available online. We apologize for any inconvenience caused.

PBC
researchProduct

Supersymmetric type-II seesaw mechanism: CERN LHC and leptón flavor violating phenomenology

2008

We study the supersymmetric version of the type-II seesaw mechanism assuming minimal supergravity boundary conditions. We calculate branching ratios for lepton flavor violating (LFV) scalar tau decays, potentially observable at the LHC, as well as LFV decays at low energy, such as l{sub i}{yields}l{sub j}+{gamma}, and compare their sensitivity to the unknown seesaw parameters. In the minimal case of only one triplet coupling to the standard model lepton doublets, ratios of LFV branching ratios can be related unambiguously to neutrino oscillation parameters. We also discuss how measurements of soft SUSY breaking parameters at the LHC can be used to indirectly extract information of the seesa…

PhysicsNuclear and High Energy PhysicsParticle physicsLarge Hadron ColliderHigh Energy Physics::PhenomenologyFísicaSupersymmetryNuclear physicsSeesaw mechanismSeesaw molecular geometrySoft SUSY breakingHigh Energy Physics::ExperimentNeutrino oscillationPhenomenology (particle physics)Lepton
researchProduct

Dark matter in minimal supergravity with type-II seesaw mechanism

2009

We calculate the relic density of the lightest neutralino in a supersymmetric seesaw type-II (``triplet seesaw'') model with minimal supergravity boundary conditions at the grand unified theory (GUT) scale. The presence of a triplet below the GUT scale, required to explain measured neutrino data in this setup, leads to a characteristic deformation of the sparticle spectrum with respect to the pure minimal supergravity (mSUGRA) expectations, affecting the calculated relic dark matter (DM) density. We discuss how the DM allowed regions in the $({m}_{0},{M}_{1/2})$ plane change as a function of the (type-II) seesaw scale. We also compare the constraints imposed on the models parameter space fo…

PhysicsNuclear and High Energy PhysicsParticle physics010308 nuclear & particles physicsSupergravityDark matterHigh Energy Physics::PhenomenologyFísicaSupersymmetry01 natural sciencesSeesaw mechanismSeesaw molecular geometry0103 physical sciencesNeutralinoGrand Unified TheoryHigh Energy Physics::ExperimentNeutrino010306 general physics
researchProduct