0000000000583183

AUTHOR

Uwe Siebert

0000-0001-6425-7671

showing 2 related works from this author

Cost effectiveness of peginterferon α-2b plus ribavirin versus interferon α-2b plus ribavirin for initial treatment of chronic hepatitis C

2003

Background: Peginterferon α-2b plus ribavirin therapy in previously untreated patients with chronic hepatitis C yields the highest sustained virological response rates of any treatment strategy but is expensive. Aims: To estimate the cost effectiveness of treatment with peginterferon α-2b plus ribavirin compared with interferon α-2b plus ribavirin for initial treatment of patients with chronic hepatitis C. Methods: Individual patient level data from a randomised clinical trial with peginterferon plus ribavirin were applied to a previously published and validated Markov model to project lifelong clinical outcomes. Quality of life and economic estimates were based on German patient data. We u…

medicine.medical_specialtyCost effectivenessbusiness.industryRibavirinGastroenterologyvirus diseasesAlpha interferonHepatitis CWirtschaftswissenschaftenmedicine.diseaseGastroenterologySurgeryQuality-adjusted life yearClinical trialchemistry.chemical_compoundchemistryInternal medicinemedicinebusinessViral loadInterferon alfamedicine.drug
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Ensuring Effective Prevention of Iodine Deficiency Disorders

2016

To access publisher's full text version of this article click on the hyperlink at the bottom of the page Programs initiated to prevent iodine deficiency disorders (IDD) may not remain effective due to changes in government policies, commercial factors, and human behavior that may affect the efficacy of IDD prevention programs in unpredictable directions. Monitoring and outcome studies are needed to optimize the effectiveness of IDD prevention. Although the need for monitoring is compelling, the current reality in Europe is less than optimal. Regular and systematic monitoring surveys have only been established in a few countries, and comparability across the studies is hampered by the lack o…

Research designmedicine.medical_specialtyNUR12StandardizationEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismOutcome assessmentKlinikai orvostudományok03 medical and health sciences0302 clinical medicineEndocrinologyHealth caremedicine030212 general & internal medicineIntensive care medicineBeneficial effectsCongenital Hypothyroidism/prevention and controlEndocrinology; Endocrinology Diabetes and Metabolismbusiness.industryIodine/deficiencyOrvostudományokmedicine.diseaseIodine deficiency3. Good healthEuropeDiabetes and Metabolismbusiness
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