The Anatomy of an Optical Biopsy Semantic Retrieval System

A case-based computer-aided diagnosis system assists physicians and other medical personnel in the interpretation of optical biopsies obtained through confocal laser endomicroscopy. Extraction in CLE images shows promising results on inferring semantic metadata from low-level features. In order to effectively ensure the interoperability with potential third-party applications, the system provides an interface compliant with the recent standards ISO/IEC 15938-12:2008 (MPEG Query Format) and ISO/IEC 24800 (JPEG Search).