0000000000589933
AUTHOR
J. J. Alegre-sancho
FRI0696 Patient activation and adherence to biological therapy: preliminary results
Background: Medication non-adherence is associated with treatment failure. Some authors show a positive relationship between patient activation and both, adherence to treatment for chronic conditions and improved outcomes. Objectives: To present preliminary results of a study measuring adherence to biological therapy and its relationship with the Patient Activation Measure (PAM) in the outpatient setting. Methods: Ambispective longitudinal observational descriptive study in a general tertiary university hospital. Patients on treatment with the same biological drug for ≥6 months were included in order of arrival. Patients with some degree of mental disability, which prevented understanding o…
FRI0662 ACTIVATION AND LEUKOCYTE ADHESION IS ASSOCIATED WITH VASCULAR DAMAGE IN PATIENTS WITH RHEUMATOID ARTHRITIS AND PSORIATIC ARTHRITIS
Background Patients with inflammatory rheumatic diseases, such as rheumatoid arthritis (RA) or psoriatic arthritis (PsA), have a higher cardiovascular risk than the general population. There are data in other pathologies about the role of leukocyte adhesion on endothelial damage. Objectives To evaluate the relationship between leukocyte adhesion and subclinical vascular damage in patients with RA and PsA. Methods Observational, cross-sectional exploratory study. Patients with RA and PsA who had at least one previous vascular study were recruited in a tertiary hospital during a period of 3 months. All of them donated a sample of fresh blood. Neutrophils were isolated and perfused on a monola…