A Biocatalytic Nanomaterial for the Label-Free Detection of Virus-Like Particles

2017

International audience; The design of nanomaterials that are capable of specific and sensitive biomolecular recognition is an on-going challenge in the chemical and biochemical sciences. A number of sophisticated artificial systems have been designed to specifically recognize a variety of targets. However, methods based on natural biomolecular detection systems using antibodies are often superior. Besides greater affinity and selectivity, antibodies can be easily coupled to enzymatic systems that act as signal amplifiers, thus permitting impressively low detection limits. The possibility to translate this concept to artificial recognition systems remains limited due to design incompatibilit…

Cover Picture: A Biocatalytic Nanomaterial for the Label-Free Detection of Virus-Like Particles (ChemBioChem 11/2017)

2017