0000000000591378

AUTHOR

Marianna Delussi

0000-0002-5888-3024

showing 2 related works from this author

Motor Cortex Function in Fibromyalgia: A Study by Functional Near-Infrared Spectroscopy

2019

Previous studies indicated changes of motor cortex excitability in fibromyalgia (FM) patients and the positive results of transcranial stimulation techniques. The present study aimed to explore the metabolism of motor cortex in FM patients, in resting state and during slow and fast finger tapping, using functional Near-Infrared Spectroscopy (fNIRS), an optical method which detects in real time the metabolism changes in the cortical tissue. We studied 24 FM patients and 24 healthy subjects. We found a significant slowness of motor speed in FM patients compared to controls. During resting state and slow movement conditions, the metabolism of the motor areas was similar between groups. The oxy…

lcsh:R5-920Article SubjectResting state fMRIbusiness.industrymotor cortex fibromyalgia near infra-red spectroscopy (NIRS)Stimulationmedicine.diseaseAnesthesiology and Pain Medicinemedicine.anatomical_structureFibromyalgiaFinger tappingmedicineFunctional near-infrared spectroscopyIn patientNeurology (clinical)Abnormalitylcsh:Medicine (General)businessNeuroscienceResearch ArticleMotor cortexPain Research and Treatment
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Effects of Botulinum Toxin A on Allodynia in Chronic Migraine: An Observational Open-Label Two-Year Study.

2019

<b><i>Background:</i></b> Onabotulinumtoxin A (OBT-A) is a treatment option for chronic migraine (CM), though the possible effect on central sensitization and allodynia is still unknown. <b><i>Aims:</i></b> The present study aimed to evaluate (1) the long-term outcome of allodynia in a group of CM treated with OBT-A (2) if the presence and severity of allodynia could predict the long-term effect of OBT-A (3) if the improvement of allodynia, could contribute to the clinical efficacy of OBT-A. <b><i>Methods:</i></b> This was an observational, open-label, cohort study conducted on 99 CM patients treated for 1 year and 44 p…

AdultMaleMigraine Disorders030204 cardiovascular system & hematologyAllodyniaCohort Studies03 medical and health sciences0302 clinical medicineChronic MigraineBotulinum toxinMedicineHumansBotulinum Toxins Type ADepression (differential diagnoses)Chronic migrainebusiness.industrymusculoskeletal neural and ocular physiologyCentral sensitizationMiddle Agedmedicine.diseaseBotulinum toxinSleep deprivationNociceptionAllodyniaTreatment OutcomeNeurologyMigraineNeuromuscular AgentsHyperalgesiaAnesthesiaAnxietyFemaleNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgerymedicine.drugEuropean neurology
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