0000000000595046

AUTHOR

Sinan Nazlim

showing 2 related works from this author

Odontogenic tumors: a collaborative study of 218 cases diagnosed over 12 years and comprehensive review of the literature.

2015

Objectives: The objective of this study was to analyze the frequency and distribution of odontogenic tumors (OTs) in the Cappadocia region of Turkey, and to compare the findings with those reported in the literature. Study Design: The records of the Oral and Maxillofacial Surgery and Pathology Departments at Erciyes University, with histologic diagnosis of odontogenic tumors (based on the World Health Organization classification, 2005), over a 12-year period, were analyzed. The relative frequency of different types of tumors was also analyzed and compared with the literature. Results: OTs in the present study constituted 2.74% of all the 7,942 registered biopsies. A total of 218 cases of OT…

AdultMalemedicine.medical_specialtyTime Factorsgenetic structuresAdolescentTurkeyDentistryOdontologíaOdontogenic TumorsJaw neoplasmOdontogenic myxomaYoung AdultOdontomaMedicineHumansAmeloblastomaChildGeneral DentistryAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologybusiness.industryResearchOdontogenic tumorRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludDermatologyJaw NeoplasmsOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgerySurgeryKeratocystic Odontogenic TumorFemalebusinessMedicina oral, patologia oral y cirugia bucal
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A c.1244G>A (p.Arg415Gln) mutation in SH3BP2 gene causes cherubism in a Turkish family: report of a family with review of the literature

2014

Objectives: The present study was aimed at advancing the understanding of the pathogenesis of cherubism by presenting a case study based on history, physical examination, typical radiological features, molecular and histo - pathological laboratory tests and a review of the literature. Study Design: This study began with a 7-year-old boy who was referred due to mandibular overgrowth. A pan - oramic radiograph revealed multilocular radiolucent lesions of the upper/lower jaws suggestive of cherubism. Overall, a total of four family members were tested for SH3BP2 mutations, namely two siblings and their parents. Both siblings had been clinically diagnosed with cherubism; however, the parents we…

MalePathologymedicine.medical_specialtyTurkeyPhysical examinationOdontologíaDiseaseExonSH3BP2medicineMissense mutationHumansChildGeneral DentistryPathologicalGenetic associationAdaptor Proteins Signal TransducingOral Medicine and Pathologymedicine.diagnostic_testbusiness.industryResearchCherubismmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludCherubismPedigreePhenotypeOtorhinolaryngologyChild PreschoolMutationUNESCO::CIENCIAS MÉDICASSurgeryFemalebusiness
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