0000000000595534

AUTHOR

Nuria Maroto

showing 3 related works from this author

Short-term effectiveness of golimumab for ulcerative colitis: Observational multicenter study

2016

AIM To evaluate the real-world effectiveness of golimumab in ulcerative colitis (UC) and to identify predictors of response. METHODS We conducted an observational, prospective and multi-center study in UC patients treated with golimumab, from September 2014 to September 2015. Clinical activity was assessed at wk 0 and 14 with the physician' s global clinical assessment (PGA) and the partial Mayo score. Colonoscopies and blood tests were performed, following daily-practice clinical criteria, and the results were recorded in an SPSS database. RESULTS Thirty-three consecutive patients with moderately to severely active UC were included. Among them, 54.5% were female and 42 years was the averag…

AdultMalemedicine.medical_specialtyTime FactorsAnti-Inflammatory AgentsObservational StudySeverity of Illness IndexGolimumab03 medical and health sciences0302 clinical medicineGastrointestinal AgentsAdrenal Cortex HormonesInternal medicineHumansMedicineProspective StudiesTumor Necrosis Factor-alphabusiness.industryRemission InductionGastroenterologyAntibodies MonoclonalColonoscopyGeneral MedicineMiddle Agedmedicine.diseaseReal-life resultsUlcerative colitisdigestive system diseasesGolimumabTreatment OutcomeMulticenter studyUlcerative colitisSpain030220 oncology & carcinogenesisColitis UlcerativeDrug Therapy CombinationFemale030211 gastroenterology & hepatologyObservational studybusinessmedicine.drug
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Inflammatory bowel disease in patients over the age of 70y. Does the disease duration influence its behavior?

2018

Introduction: The fastest growing segment of our population is that of people above 70 years of age. Elderly patients with IBD exhibit several specific problems. Our objective was to evaluate the clinical course, the side effects of the treatments and the need for surgery of elderly patients, regardless of the age of onset.Materials and Methods: This was a cross-sectional study wherein retrospective data were collected from multiple centers from seven hospitals within the Valencia metropolitan area. Data were collected on patients older than 70y with inflammatory bowel disease.Results: We identified a total of 331 patients older than 70 years of age (5.3% of patients monitored at our center…

Malemedicine.medical_specialtyDisease durationPopulationComorbiditymacromolecular substancesInflammatory bowel diseaseGastroenterology03 medical and health sciencesElderly0302 clinical medicineAdrenal Cortex HormonesNeoplasmsInternal medicinemedicineHumansImmunologic FactorsIn patientMesalamineeducationAgedRetrospective Studiesulcerative colitisAged 80 and overCrohn's diseaseeducation.field_of_studybusiness.industrymusculoskeletal neural and ocular physiologyGastroenterologyInflammatory Bowel Diseasesmedicine.diseaseUlcerative colitisCrohn's diseaseCross-Sectional StudiesLogistic ModelsSpainSurgical Procedures Operative030220 oncology & carcinogenesisDisease ProgressionFemale030211 gastroenterology & hepatologybusiness
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Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study

2021

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD—Crohn’s disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)—during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and…

Crohn’s diseasemedicine.medical_specialtyPopulationDiseaseInflammatory bowel diseasedigestive systemArticle03 medical and health sciences0302 clinical medicineInterquartile rangeinflammatory bowel diseaseInternal medicineEpidemiologyMedicineeducationCrohn’s disease epidemiology incidence inflammatory bowel disease ulcerative colitisulcerative colitisCrohn's diseaseeducation.field_of_studybusiness.industryIncidence (epidemiology)RGeneral Medicinemedicine.diseaseUlcerative colitisdigestive system diseasesCrohn's disease030220 oncology & carcinogenesisincidenceMedicine030211 gastroenterology & hepatologyepidemiologybusiness
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