0000000000595607

AUTHOR

Hans P. Eser

showing 2 related works from this author

Influence of sample preparation on analytical results: drug analysis [GC/MS] on hair snippets versus hair powder using various extraction methods

1997

The comparison of aqueous extraction methods and hair extraction by organic solvents performed on hair powder as well as on hair snippets of the same sample revealed different qualities of the procedures. Qualitative and quantitative results by the same derivatization step and GC/MS detection demonstrated, that the risk of missing a drug substance is higher using hair snippets than after drug extraction on pulverised hair. Drug recovery for opiates, cocaine and benzoylecgonine from hair was found to be best in aqueous solvents or in methanol extracts. The results are discussed under the aspects of solid-phase extraction, the hair sample representing an inhomogenous material. The localisatio…

NarcoticsAqueous solutionChromatographyintegumentary systemChemistryHair analysisPilot ProjectsGas Chromatography-Mass SpectrometryPathology and Forensic MedicineSubstance Abuse DetectionSolventchemistry.chemical_compoundSolventsotorhinolaryngologic diseasesBenzoylecgonineHumansSample preparationsense organsGas chromatographyGas chromatography–mass spectrometryDerivatizationLawHairForensic Science International
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Zum Suchtmittelnachweis in Haaren. VII. Untersuchungen bei Methadonpatienten unter konstanter Wirkstoffeinnahme

1998

Bei 18 Patienten unter Methadonsubstitutionstherapie mit konstanter Dosis konnte bei Berucksichtigung des individuellen Haarwachstums keine zufriedenstellende Korrelation (r = 0,602) zwischen Aufnahmemenge und Methadongehalt im Haar gefunden werden. Die uber 4 Tage durchgefuhrten Sammeltests mit Perspirationspflaster bestatigten das Vorhandensein von Methadon und seinem Hauptmetaboliten auf der Hautoberflache und zeigten bei 6 Personen einen Beikonsum, dessen Substanzspektrum teilweise auch in den untersuchten Haarabschnitten nachzuweisen war.

Gynecologymedicine.medical_specialtymedia_common.quotation_subjectmedicineArtPathology and Forensic Medicinemedia_commonRechtsmedizin
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