0000000000595711

AUTHOR

Isabella Russo

showing 2 related works from this author

miRNome Profiling Detects miR-101-3p and miR-142-5p as Putative Blood Biomarkers of Frailty Syndrome

2022

Frailty is an aging-related pathology, defined as a state of increased vulnerability to stressors, leading to a limited capacity to meet homeostatic demands. Extracellular microRNAs (miRNAs) were proposed as potential biomarkers of various disease conditions, including age-related pathologies. The primary objective of this study was to identify blood miRNAs that could serve as potential biomarkers and candidate mechanisms of frailty. Using the Fried index, we enrolled 22 robust and 19 frail subjects. Blood and urine samples were analysed for several biochemical parameters. We observed that sTNF-R was robustly upregulated in the frail group, indicating the presence of an inflammatory state. …

smRNA-seqmicroRNAFrailtymiR-142-5pBiomarkers; Frailty; MicroRNA; MiR-101-3p; MiR-142-5p; MiRNome; RNA-seq; SmRNA-seqbiomarkersmiRNomeReal-Time Polymerase Chain ReactionmicroRNA; frailty; smRNA-seq; miRNome; biomarkers; RNA-seq; miR-101-3p; miR-142-5pMicroRNAsGeneticsbiomarkerHumansRNA-seq; biomarkers; frailty; miR-101-3p; miR-142-5p; miRNome; microRNA; smRNA-seq; Biomarkers; Humans; Real-Time Polymerase Chain Reaction; Frailty; MicroRNAsRNA-seqmiR-101-3pGenetics (clinical)Genes; Volume 13; Issue 2; Pages: 231
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40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

2004

0303 health sciencesmedicine.medical_specialtybusiness.industryEASDEndocrinology Diabetes and MetabolismHuman physiologymedicine.disease03 medical and health sciences0302 clinical medicineDiabetes mellitusFamily medicineInternal MedicineMedicinebusiness030217 neurology & neurosurgery030304 developmental biology
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