0000000000595877

AUTHOR

Zoya Hojabri

showing 2 related works from this author

Molecular epidemiology of Acinetobacter baumannii in Iran: endemic and epidemic spread of multiresistant isolates

2014

Objectives We examined the molecular epidemiology of Acinetobacter baumannii clinical isolates from two cities (Tehran and Tabriz) of Iran. Methods DiversiLab repetitive extragenic palindromic PCR (rep-PCR), multilocus sequence typing and sequence group multiplex PCR were performed. The presence of resistance mechanisms including metallo-β-lactamases, extended-spectrum β-lactamases, OXA carbapenemases, aminoglycoside-modifying enzymes and RNA methylases was also investigated. Results DiversiLab rep-PCR identified 11 clusters and 11 singleton isolates. Twelve sequence types (STs), including six novel types, were identified. Sequence groups (SGs) 1-3 as well as five additional banding pattern…

Acinetobacter baumanniiMicrobiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaGenotypeIranBiologySettore MED/42 - Igiene Generale E ApplicataMicrobiologySequence-tagged siteDrug Resistance Multiple BacterialMultiplex polymerase chain reactionCluster AnalysisHumansPharmacology (medical)CitiesPharmacologyGeneticsMolecular EpidemiologyMolecular epidemiologyGenetic VariationOutbreakbiology.organism_classificationTRNA MethyltransferasesAcinetobacter baumanniiMolecular TypingMultiple drug resistanceAcinetobacter baumannii MDR Iran molecular epidemiologyInfectious DiseasesMultilocus sequence typingAcinetobacter InfectionsJournal of Antimicrobial Chemotherapy
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In vitro activities of tetracyclines against different clones of multidrug-resistant Acinetobacter baumannii isolates from two Iranian hospitals.

2014

Acinetobacter baumannii has emerged as one of the most challenging healthcare-related pathogens and its occurrence has increased worldwide, especially in patients admitted to intensive care units. A. baumannii isolates are frequently resistant to multiple antimicrobial agents and there are recent reports of isolates resistant to virtually all clinically relevant drugs. In the present study, the in vitro activities of tigecycline, minocycline and doxycycline against 67 MDR-AB isolates recovered from 29 burn and 38 non-burn Iranian patients hospitalised in Tehran and Tabriz, respectively, were studied. Tigecycline and minocycline may be still considered effective therapeutic options for MDR-A…

Microbiology (medical)Acinetobacter baumanniiSettore MED/07 - Microbiologia E Microbiologia ClinicaGenotypeGeneral MedicineMicrobial Sensitivity TestsBiologyIranSettore MED/42 - Igiene Generale E ApplicataIn vitroHospitalsMicrobiologyAnti-Bacterial AgentsMolecular TypingInfectious DiseasesGenes BacterialTetracyclinesDrug Resistance Multiple BacterialHumansPharmacology (medical)Multidrug resistant Acinetobacter baumanniiAcinetobacter baumannii tetracyclines multiresistance IranAcinetobacter InfectionsInternational journal of antimicrobial agents
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